Multidrug resistance as a cause of steroid-nonresponsive downgrading type I reaction in Hansen's disease.


Journal

International journal of mycobacteriology
ISSN: 2212-554X
Titre abrégé: Int J Mycobacteriol
Pays: India
ID NLM: 101615660

Informations de publication

Date de publication:
Historique:
entrez: 13 9 2019
pubmed: 13 9 2019
medline: 28 1 2020
Statut: ppublish

Résumé

While Type 1 reaction in Hansen's disease is commonly encountered, the triggers and reasons for its persistence are not well understood even though the immunological milieu and cytokine interplay have been studied. Herein, we present a case of Type 1 downgrading reaction in which multidrug resistance was the probable cause of steroid-nonresponsiveness and which responded promptly on starting alternate antileprosy treatment.

Identifiants

pubmed: 31512611
pii: IntJMycobacteriol_2019_8_3_305_266492
doi: 10.4103/ijmy.ijmy_121_19
doi:

Substances chimiques

Leprostatic Agents 0
Steroids 0

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

305-308

Déclaration de conflit d'intérêts

None

Auteurs

Surabhi Sinha (S)

Department of Dermatology, STD and Leprosy, Dr. RML Hospital and PGIMER, New Delhi, India.

Kabir Sardana (K)

Department of Dermatology, STD and Leprosy, Dr. RML Hospital and PGIMER, New Delhi, India.

Diksha Agrawal (D)

Department of Dermatology, STD and Leprosy, Dr. RML Hospital and PGIMER, New Delhi, India.

Purnima Malhotra (P)

Department of Pathology, Dr. RML Hospital and PGIMER, New Delhi, India.

Mallika Lavania (M)

Department of Molecular Biology, Stanley Browne Laboratory, TLM Community Hospital, New Delhi, India.

Madhvi Ahuja (M)

Department of Molecular Biology, Stanley Browne Laboratory, TLM Community Hospital, New Delhi, India.

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Classifications MeSH