Synthesis of Modified Nucleoside Oligophosphates Simplified: Fast, Pure, and Protecting Group Free.
Journal
Journal of the American Chemical Society
ISSN: 1520-5126
Titre abrégé: J Am Chem Soc
Pays: United States
ID NLM: 7503056
Informations de publication
Date de publication:
25 09 2019
25 09 2019
Historique:
pubmed:
13
9
2019
medline:
13
9
2019
entrez:
13
9
2019
Statut:
ppublish
Résumé
Phosphoramidite analogues of modified cyclotriphosphates provide a general and step-economical synthesis of nucleoside triphosphates and analogues on scale without the need for protecting groups. These reagents enable rapid access to pure nucleoside oligophosphates and a range of other analogues that were previously difficult to obtain (e.g., NH, CH
Identifiants
pubmed: 31512870
doi: 10.1021/jacs.9b08273
pmc: PMC10044464
mid: NIHMS1839842
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
15013-15017Subventions
Organisme : NCI NIH HHS
ID : R01 CA031845
Pays : United States
Commentaires et corrections
Type : ErratumIn
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