Three new bioactive flavonoid glycosides from Viscum album.

Antineoplastic Agents / chemistry Cell Line, Tumor Cell Survival / drug effects Flavonoids / chemistry Glycosides / chemistry Humans Molecular Structure Plant Components, Aerial / chemistry Plant Extracts / chemistry Viscum album / chemistry
Cytotoxic activities Flavonoid glycosides Viscum album

Journal

Chinese journal of natural medicines
ISSN: 1875-5364
Titre abrégé: Chin J Nat Med
Pays: China
ID NLM: 101504416

Informations de publication

Date de publication:
Jul 2019
Historique:
received: 26 03 2019
entrez: 14 9 2019
pubmed: 14 9 2019
medline: 6 2 2020
Statut: ppublish

Résumé

Two new flavonoid glycosides, named viscumneoside XII (1), and viscumneoside XIII (2); a new dihydrogen flavonoid glycoside product named viscumneoside XIV (3), were isolated from the aerial part of Viscum album, along with seven known compounds (4-10). Their structures were identified by analysis of spectroscopic data. In addition, cytotoxicity assay showed that 1, 2 and 3 possessed significant inhibitory activities against C6, A549 and MDA-MB-231 (the inhibition rate arrived about 50%, 70% and 74% respectively with IC

Identifiants

DOI: 10.1016/S1875-5364(19)30076-7 PMID: 31514986
pubmed: 31514986
pii: S1875-5364(19)30076-7
doi: 10.1016/S1875-5364(19)30076-7
pii:
doi:

Substances chimiques

Antineoplastic Agents 0
Flavonoids 0
Glycosides 0
Plant Extracts 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

545-550

Informations de copyright

Copyright © 2019 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

Auteurs

Jia-Kun Dai (JK)

The College of Life Science, Northwest University, Xi'an 710069, China; Bio-Agriculture Institute of Shaanxi, Xi'an 710043, China.

Duo Cao (D)

The College of Life Science, Northwest University, Xi'an 710069, China; State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, Shanghai 201203, China; The College of Life Science, Yan'an University, Yan'an 710000, China. Electronic address: caoduo2013@163.com.

Cui-Hua Li (CH)

The College of Life Science, Northwest University, Xi'an 710069, China.

Jing Gao (J)

The College of Life Science, Northwest University, Xi'an 710069, China.

Meng-Qing Li (MQ)

The College of Life Science, Northwest University, Xi'an 710069, China.

Na Fan (N)

The College of Life Science, Northwest University, Xi'an 710069, China; College of Healthy Management, Shangluo University, Shangluo 726000, China.

Ya-Hui Wei (YH)

The College of Life Science, Northwest University, Xi'an 710069, China. Electronic address: weiyahui@nwu.edu.cn.

Zheng-Liang Sun (ZL)

Shanghai University of Medicine & Health Sciences Affiliated Sixth People's Hospital South Campus, Shanghai 201499, China. Electronic address: sunzl6@126.com.

Meng-Yang Hou (MY)

School of Life Science and Biotechnology, Dalian University of Technology, Dalian 116024, China.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Three new bioactive flavonoid glycosides from...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Three new bioactive flavonoid glycosides from...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire › Three new bioactive flavonoid glycosides from...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › 4H-1-Benzopyran-4-ones › Flavonoïdes › Three new bioactive flavonoid glycosides from...
questionsmedicales.fr › Glucides › Hétérosides › Three new bioactive flavonoid glycosides from...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Three new bioactive flavonoid glycosides from...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Three new bioactive flavonoid glycosides from...
questionsmedicales.fr › Structures de plante › Parties aériennes de plante › Three new bioactive flavonoid glycosides from...
questionsmedicales.fr › Préparations pharmaceutiques › Extraits de plantes › Three new bioactive flavonoid glycosides from...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Santalaceae › Viscum › Viscum album › Three new bioactive flavonoid glycosides from...