In sickness and in health: Living HIV positive kidney donation from a wife to her husband, with 7 years' post-transplant follow-up.
AIDS-Associated Nephropathy
/ complications
Acute Kidney Injury
/ etiology
Anti-HIV Agents
/ administration & dosage
Follow-Up Studies
HIV Seropositivity
/ diagnosis
HIV-1
/ isolation & purification
Humans
Kidney Transplantation
/ legislation & jurisprudence
Living Donors
Male
Middle Aged
Preoperative Care
/ methods
Spouses
Tissue and Organ Procurement
/ legislation & jurisprudence
Treatment Outcome
Viral Load
/ drug effects
Virus Replication
/ drug effects
human immunodeficiency virus
kidney transplantation
living kidney donor
Journal
Transplant infectious disease : an official journal of the Transplantation Society
ISSN: 1399-3062
Titre abrégé: Transpl Infect Dis
Pays: Denmark
ID NLM: 100883688
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
05
06
2019
revised:
04
08
2019
accepted:
01
09
2019
pubmed:
14
9
2019
medline:
1
5
2020
entrez:
14
9
2019
Statut:
ppublish
Résumé
Human immunodeficiency virus (HIV) infection was traditionally considered an absolute contraindication for kidney transplantation. After the introduction of ART, several studies have demonstrated comparable patient and graft outcomes between HIV-negative and HIV-positive kidney recipients. The US Congress passed the HIV Organ Policy Equity (HOPE) Act in 2013, which permits research in the area of HIV-positive to HIV-positive transplantation. HIV-infected living donation is also permitted under the HOPE Act. However, there is a concern regarding the safety of kidney donation in an HIV-infected person, given the risk of renal disease associated with HIV infection. We report here the case of successful kidney transplantation from HIV-positive living donor to HIV-positive recipient performed in our center on July 2012. To the best of our knowledge, this is the earliest case done in this medical context to be reported in the literature, therefore, potentially carrying several important messages to the transplantation community. In the present case, the living-donor kidney transplant was performed between a married couple infected with same strain of HIV-1, both on effective ART with efficiently suppressed viral replication and satisfactory pre-transplantation immune status.
Substances chimiques
Anti-HIV Agents
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13171Informations de copyright
© 2019 Wiley Periodicals, Inc.
Références
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