Relationship between Patient Age and Disease Features in a Prospective Cohort of 1560 Women Affected by Endometriosis.


Journal

Journal of minimally invasive gynecology
ISSN: 1553-4669
Titre abrégé: J Minim Invasive Gynecol
Pays: United States
ID NLM: 101235322

Informations de publication

Date de publication:
Historique:
received: 24 05 2019
revised: 15 08 2019
accepted: 01 09 2019
pubmed: 14 9 2019
medline: 22 12 2020
entrez: 14 9 2019
Statut: ppublish

Résumé

To assess the relationship between age, location of the disease, and surgical procedures performed in patients undergoing surgical management of endometriosis. Retrospective study using data prospectively recorded in the North-West Inter Regional Female Cohort for Patients with Endometriosis database. University tertiary referral center. Women who underwent surgical management of symptomatic endometriosis between April 2009 and April 2014. Patients were allocated to 6 groups according to their age at the time of surgery: ≤20, 21 to 25, 26 to 30, 31 to 35, 36 to 40 and >40 years. Patient characteristics, prior history, location of endometriotic lesions, stage of disease, intraoperative findings, and surgical procedures were retrieved from a prospectively recorded database. Patient characteristics, symptoms, location of endometriosis, and type of surgery performed were compared between groups. In total, 1560 procedures were performed. Of these, more than one-half were carried out in women between the age of 26 to 35 years and the majority were performed in women aged between 26 and 30 years. Only 2% of procedures were performed in women under the age of 20 years. The mean stage of the disease at the time of surgical diagnosis was stage II for women younger than 20 years, stage III for those in the age group of 21 to 25 years, and stage IV for those older than 26 years. The rate of diagnosis of deep colorectal nodules increased progressively from 20 to 26 years and remained stable thereafter. Our data confirm that endometriosis is a disease that probably progresses from adolescence until the adult period when symptoms (pain or infertility) become debilitating and require surgery. Our data suggest that policies relating to the prevention and early diagnosis of endometriosis should focus on women younger than 25 years.

Identifiants

pubmed: 31518709
pii: S1553-4650(19)30414-5
doi: 10.1016/j.jmig.2019.09.004
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1158-1166

Informations de copyright

Copyright © 2019 AAGL. Published by Elsevier Inc. All rights reserved.

Auteurs

Emanuela Stochino-Loi (E)

Expert Center in the Diagnosis and Multidisciplinary Management of Endometriosis, Department of Obstetrics and Gynecology, Rouen University Hospital, Rouen, France (Drs. Stochino-Loi, Millochau, Touleimat, Abo, and Hennetier); Service de Gynecology and Obstetrics, HFR, Fribourg Hospital Cantonal, Fribourg, Switzerland (Dr. Stochino-Loi).

Jenny-Claude Millochau (JC)

Expert Center in the Diagnosis and Multidisciplinary Management of Endometriosis, Department of Obstetrics and Gynecology, Rouen University Hospital, Rouen, France (Drs. Stochino-Loi, Millochau, Touleimat, Abo, and Hennetier).

Stefano Angioni (S)

Division of Gynecology and Obstetrics, Department of Surgical Sciences, Rouen University Hospital, Rouen, France (Dr. Angioni).

Salma Touleimat (S)

Expert Center in the Diagnosis and Multidisciplinary Management of Endometriosis, Department of Obstetrics and Gynecology, Rouen University Hospital, Rouen, France (Drs. Stochino-Loi, Millochau, Touleimat, Abo, and Hennetier).

Carole Abo (C)

Expert Center in the Diagnosis and Multidisciplinary Management of Endometriosis, Department of Obstetrics and Gynecology, Rouen University Hospital, Rouen, France (Drs. Stochino-Loi, Millochau, Touleimat, Abo, and Hennetier).

Isabella Chanavaz-Lacheray (I)

Endometriosis Center, Clinique Tivoli-Ducos, Bordeaux, France (Drs. Roman and Chanavaz-Lacheray).

Clotilde Hennetier (C)

Expert Center in the Diagnosis and Multidisciplinary Management of Endometriosis, Department of Obstetrics and Gynecology, Rouen University Hospital, Rouen, France (Drs. Stochino-Loi, Millochau, Touleimat, Abo, and Hennetier).

Horace Roman (H)

Endometriosis Center, Clinique Tivoli-Ducos, Bordeaux, France (Drs. Roman and Chanavaz-Lacheray); Department of Gynecology and Obstetrics, Aarhus University Hospital, Aarhus, Denmark (Dr. Roman). Electronic address: horace.roman@gmail.com.

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