Latest developments in post-mortem foetal imaging.
Journal
Prenatal diagnosis
ISSN: 1097-0223
Titre abrégé: Prenat Diagn
Pays: England
ID NLM: 8106540
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
received:
18
07
2019
revised:
29
08
2019
accepted:
07
09
2019
pubmed:
17
9
2019
medline:
27
1
2021
entrez:
17
9
2019
Statut:
ppublish
Résumé
A sustained decline in parental consent rates for perinatal autopsies has driven the development of less-invasive methods for death investigation. A wide variety of imaging modalities have been developed for this purpose and include post-mortem whole body magnetic resonance imaging (MRI), ultrasound, computed tomography (CT) and micro-focus CT techniques. These are also vital for "minimally invasive" methods, which include potential for tissue sampling, such as image guidance for targeted biopsies and laparoscopic-assisted techniques. In this article, we address the range of imaging techniques currently in clinical practice and those under development. Significant advances in high-field MRI and micro-focus CT imaging show particular promise for smaller and earlier gestation foetuses. We also review how MRI biomarkers such as diffusion-weighted imaging and organ volumetric analysis may aid diagnosis and image interpretation in the absence of autopsy data. Three-dimensional printing and augmented reality may help make imaging findings more accessible to parents, colleagues and trainees.
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
28-37Subventions
Organisme : Department of Health
ID : 14/168/02
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R002118/1
Pays : United Kingdom
Organisme : Department of Health
ID : NIHR-CDF-2017-10-037
Pays : United Kingdom
Organisme : Department of Health
ID : CDF-2017-10-037
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/R00218/1
Pays : United Kingdom
Organisme : Department of Health
ID : NIHR-CS-012-002
Pays : United Kingdom
Organisme : Department of Health
ID : ICA-CDRF-2017-03-053
Pays : United Kingdom
Informations de copyright
© 2019 John Wiley & Sons, Ltd.
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