Management of Malignant Pleural Effusions-What Is New.
Biopsy
/ methods
Catheters, Indwelling
Chest Tubes
Drainage
/ methods
Health Expenditures
Humans
Manometry
Pleural Effusion, Malignant
/ diagnosis
Pleurodesis
/ methods
Practice Guidelines as Topic
Quality of Life
Thoracentesis
/ methods
Thrombolytic Therapy
/ methods
Ultrasonography, Interventional
/ methods
Journal
Seminars in respiratory and critical care medicine
ISSN: 1098-9048
Titre abrégé: Semin Respir Crit Care Med
Pays: United States
ID NLM: 9431858
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
entrez:
17
9
2019
pubmed:
17
9
2019
medline:
28
4
2020
Statut:
ppublish
Résumé
Malignant pleural effusion (MPE) is a common and challenging problem. Patients affected by MPE have a poor prognosis and suffer from breathlessness and impaired quality of life. The management of MPE has barely changed for many decades; however, recent research has driven new paradigms in the diagnosis and treatment of MPE and stimulated novel concepts that are being evaluated in many ongoing studies. This review provides an overview of recent advances in the diagnosis of MPE, including new cytopathology and imaging techniques, and the landmark studies that provide a solid evidence base to support the use of indwelling pleural catheters as first-line treatment in MPE. Lingering management dilemmas, including optimal chest drainage tube and role of surgery in MPE, and key knowledge gaps that are the focus of ongoing research are also highlighted.
Identifiants
pubmed: 31525808
doi: 10.1055/s-0039-1698285
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
323-339Informations de copyright
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Déclaration de conflit d'intérêts
Y.C.G.L. has served on the advisory board of CareFusion/BD. He led the AMPLE-2 and AMPLE-3 clinical trials for which Rocket Med Plc has provided an unrestricted education grant and also drainage kits without charge for participants. F.M. has received unrestricted education grant for research from Centurion, Inc. R.T. and B.R. have no conflict of interest to declare.