Translational glycobiology: from bench to bedside.
Allergy
immunology
Journal
Journal of the Royal Society of Medicine
ISSN: 1758-1095
Titre abrégé: J R Soc Med
Pays: England
ID NLM: 7802879
Informations de publication
Date de publication:
10 2019
10 2019
Historique:
pubmed:
19
9
2019
medline:
23
1
2020
entrez:
19
9
2019
Statut:
ppublish
Résumé
The importance of sugars to protein function is real and is of significant clinical relevance. Technology advances enable large population studies to be carried out, shedding light on individual sugar variation and variations with time. Three-dimensional mass spectroscopy on solid pathological specimens is going to open up a whole new world of pathology visualisation. The door is now open to exploit carbohydrate recognition in new therapeutics by identifying novel biomarkers in cancer to aid diagnosis, and also providing therapeutic targets for treatment. Glycan age correlates with biological age. This means we can map the reversal of biological age with exercise and diet.
Identifiants
pubmed: 31526214
doi: 10.1177/0141076819865863
pmc: PMC6794674
doi:
Substances chimiques
Polysaccharides
0
Proteins
0
Sugars
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
424-427Références
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