Moving Beyond 'Therapy' and 'Enhancement' in the Ethics of Gene Editing.
enhancement
gene editing
genetics
reproductive medicine
research ethics
translational research
Journal
Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees
ISSN: 1469-2147
Titre abrégé: Camb Q Healthc Ethics
Pays: United States
ID NLM: 9208482
Informations de publication
Date de publication:
10 2019
10 2019
Historique:
entrez:
19
9
2019
pubmed:
19
9
2019
medline:
7
8
2020
Statut:
ppublish
Résumé
Since the advent of recombinant DNA technology, expectations (and trepidations) about the potential for altering genes and controlling our biology at the fundamental level have been sky high. These expectations have gone largely unfulfilled. But though the dream (or nightmare) of being able to control our biology is still far off, gene editing research has made enormous strides toward potential clinical use. This paper argues that when it comes to determining permissible uses of gene editing in one important medical context-germline intervention in reproductive medicine-issues about enhancement and eugenics are, for the foreseeable future, a red herring. Current translational goals for gene editing research involve a different kind of editing than would be required to achieve manipulation of complex traits such as intelligence, and there are more pressing (and unresolved) questions that need attention if clinical use of gene editing in reproductive medicine ever becomes a possibility.
Identifiants
pubmed: 31526421
doi: 10.1017/S0963180119000641
pii: S0963180119000641
pmc: PMC6751566
mid: NIHMS1033303
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
695-707Subventions
Organisme : NHGRI NIH HHS
ID : R03 HG010417
Pays : United States