Infiltrating Myeloid Cells Drive Osteosarcoma Progression via GRM4 Regulation of IL23.

Animals Bone Neoplasms / genetics Cell Line, Tumor Disease Progression Humans Interleukin-12 / metabolism Interleukin-23 Subunit p19 / genetics Mice Myeloid Cells / immunology Neoplasm Transplantation Osteosarcoma / genetics Receptors, Metabotropic Glutamate / genetics Survival Analysis Up-Regulation

Journal

Cancer discovery
ISSN: 2159-8290
Titre abrégé: Cancer Discov
Pays: United States
ID NLM: 101561693

Informations de publication

Date de publication:
11 2019
Historique:
received: 03 02 2019
revised: 03 06 2019
accepted: 18 07 2019
pubmed: 19 9 2019
medline: 22 8 2020
entrez: 19 9 2019
Statut: ppublish

Résumé

The glutamate metabotropic receptor 4 (

Identifiants

DOI: 10.1158/2159-8290.CD-19-0154 PMID: 31527131
pubmed: 31527131
pii: 2159-8290.CD-19-0154
doi: 10.1158/2159-8290.CD-19-0154
doi:

Substances chimiques

IL23A protein, human 0
Interleukin-23 Subunit p19 0
Receptors, Metabotropic Glutamate 0
Interleukin-12 187348-17-0
metabotropic glutamate receptor 4 YZN9W7P1BX

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1511-1519

Commentaires et corrections

Type : CommentIn

Informations de copyright

©2019 American Association for Cancer Research.

Auteurs

Maya Kansara (M)

The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia. m.kansara@garvan.org.au d.thomas@garvan.org.au.
St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, New South Wales, Australia.

Kristian Thomson (K)

The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.
ORCID: 0000-0002-9509-9036

Puiyi Pang (P)

The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

Aurelie Dutour (A)

Cancer Research Center of Lyon, INSERM UMR 1052, CNRS UMR 5286, Centre Leon Berard, Lyon, France.

Lisa Mirabello (L)

Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, Maryland.

Francine Acher (F)

IGF, Universite de Montpellier, CNRS, INSERM, Montpellier, France.
ORCID: 0000-0002-5413-4181

Jean-Philippe Pin (JP)

Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, CNRS UMR8601, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

Elizabeth G Demicco (EG)

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada.

Juming Yan (J)

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
ORCID: 0000-0003-0857-8870

Michele W L Teng (MWL)

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
ORCID: 0000-0003-1886-9145

Mark J Smyth (MJ)

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

David M Thomas (DM)

The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia. m.kansara@garvan.org.au d.thomas@garvan.org.au.
St. Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, New South Wales, Australia.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Maladies ostéomusculaires › Maladies osseuses › Tumeurs osseuses › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Évolution de la maladie › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-12 › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-23 › Sous-unité p19 de l'interleukine-23 › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Cellules › Cellules myéloïdes › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Techniques d'investigation › Transplantation tumorale › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu conjonctif et des tissus mous › Sarcomes › Ostéosarcome › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs aux acides aminés › Récepteurs au glutamate › Récepteurs métabotropes au glutamate › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Analyse de survie › Infiltrating Myeloid Cells Drive Osteosarcoma...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Régulation positive › Infiltrating Myeloid Cells Drive Osteosarcoma...