Developing Protein-Based Nanoparticles as Versatile Delivery Systems for Cancer Therapy and Imaging.
cancer imaging
cancer therapy
drug delivery
nanomedicine
protein-based nanoparticles
synthetic biology
virus-like particles
Journal
Nanomaterials (Basel, Switzerland)
ISSN: 2079-4991
Titre abrégé: Nanomaterials (Basel)
Pays: Switzerland
ID NLM: 101610216
Informations de publication
Date de publication:
16 Sep 2019
16 Sep 2019
Historique:
received:
19
08
2019
revised:
04
09
2019
accepted:
12
09
2019
entrez:
19
9
2019
pubmed:
19
9
2019
medline:
19
9
2019
Statut:
epublish
Résumé
In recent years, it has become apparent that cancer nanomedicine's reliance on synthetic nanoparticles as drug delivery systems has resulted in limited clinical outcomes. This is mostly due to a poor understanding of their "bio-nano" interactions. Protein-based nanoparticles (PNPs) are rapidly emerging as versatile vehicles for the delivery of therapeutic and diagnostic agents, offering a potential alternative to synthetic nanoparticles. PNPs are abundant in nature, genetically and chemically modifiable, monodisperse, biocompatible, and biodegradable. To harness their full clinical potential, it is important for PNPs to be accurately designed and engineered. In this review, we outline the recent advancements and applications of PNPs in cancer nanomedicine. We also discuss the future directions for PNP research and what challenges must be overcome to ensure their translation into the clinic.
Identifiants
pubmed: 31527483
pii: nano9091329
doi: 10.3390/nano9091329
pmc: PMC6781024
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Cancer Institute NSW
ID : ECF171114
Organisme : ARC Centre of Excellence for Nanoscale BioPhotonics
ID : CE140100003
Organisme : Commonwealth Scientific and Industrial Research Organisation
ID : 50068016
Références
Biomacromolecules. 2011 May 9;12(5):1629-40
pubmed: 21446722
Nano Today. 2013 Oct;8(5):454-460
pubmed: 25419228
Bioconjug Chem. 2016 Oct 19;27(10):2225-2238
pubmed: 27547843
ACS Nano. 2017 Oct 24;11(10):9594-9613
pubmed: 28926225
Chem Soc Rev. 2006 Jun;35(6):512-23
pubmed: 16729145
Nanoscale. 2017 Aug 24;9(33):12096-12109
pubmed: 28799610
Asia Ocean J Nucl Med Biol. 2015 Summer;3(2):99-106
pubmed: 27408889
Expert Rev Vaccines. 2013 Feb;12(2):129-41
pubmed: 23414405
Pharm Res. 2016 Oct;33(10):2373-87
pubmed: 27299311
Chem Rev. 2015 Feb 25;115(4):1990-2042
pubmed: 25602130
Crit Rev Biotechnol. 2015 Jun;35(2):209-21
pubmed: 24102113
J Control Release. 2018 Apr 10;275:177-185
pubmed: 29474961
J Control Release. 2007 Jul 16;120(1-2):41-50
pubmed: 17512998
Mol Pharm. 2015 May 4;12(5):1422-30
pubmed: 25811429
ACS Nano. 2018 Jan 23;12(1):24-43
pubmed: 29257865
Mol Pharm. 2013 Jan 7;10(1):33-42
pubmed: 22731633
Biomacromolecules. 2016 Feb 8;17(2):514-22
pubmed: 26686226
Cold Spring Harb Perspect Biol. 2013 Nov 01;5(11):a016980
pubmed: 24186069
Nat Rev Cancer. 2003 May;3(5):380-7
pubmed: 12724736
Drug Deliv. 2017 Dec;24(sup1):22-32
pubmed: 29069920
Cancers (Basel). 2017 Feb 18;9(2):
pubmed: 28218708
ACS Nano. 2016 Aug 23;10(8):7314-22
pubmed: 27351374
Oncotarget. 2016 Sep 13;7(37):59402-59416
pubmed: 27449085
Adv Drug Deliv Rev. 2016 Nov 15;106(Pt A):157-171
pubmed: 26994591
Bubble Sci Eng Technol. 2009 Nov;1(1-2):3-17
pubmed: 20574549
Biotechnol Adv. 2020 Sep - Oct;42:107339
pubmed: 30639928
Bioeng Transl Med. 2017 Jan 19;2(1):43-57
pubmed: 29313023
Genes (Basel). 2018 Jul 23;9(7):
pubmed: 30041491
J Control Release. 2015 Feb 28;200:138-57
pubmed: 25545217
N Engl J Med. 1986 Dec 25;315(26):1650-9
pubmed: 3537791
Biomacromolecules. 2014 Oct 13;15(10):3794-801
pubmed: 25180761
Small. 2016 Apr 6;12(13):1758-69
pubmed: 26853911
Int J Nanomedicine. 2017 Apr 18;12:3137-3151
pubmed: 28458536
Biomaterials. 2018 Jan;152:37-46
pubmed: 29107217
Nat Rev Cancer. 2010 Jul;10(7):505-14
pubmed: 20574450
Nat Commun. 2018 Apr 12;9(1):1410
pubmed: 29650952
Nat Rev Cancer. 2017 Jan;17(1):20-37
pubmed: 27834398
Macromol Biosci. 2018 May;18(5):e1800013
pubmed: 29665276
Adv Drug Deliv Rev. 2017 Jan 1;108:25-38
pubmed: 27137110
J Control Release. 2016 Oct 10;239:10-8
pubmed: 27524282
Mol Pharm. 2018 Aug 6;15(8):3595-3599
pubmed: 29966416
J Nanosci Nanotechnol. 2008 May;8(5):2316-22
pubmed: 18572643
Adv Mater. 2014 Dec 3;26(45):7615-21
pubmed: 25328159
Virology. 2014 Jan 20;449:163-73
pubmed: 24418549
Nanomedicine. 2015 Nov;11(8):1893-907
pubmed: 26282377
Curr Opin Biotechnol. 2014 Aug;28:75-82
pubmed: 24832078
PET Clin. 2016 Oct;11(4):xi-xii
pubmed: 27593253
J Biotechnol. 2017 Jul 20;254:34-42
pubmed: 28591619
J Am Chem Soc. 2010 Nov 3;132(43):15351-8
pubmed: 20942456
Oncotarget. 2016 Apr 26;7(17):23988-4004
pubmed: 26992211
J Am Chem Soc. 2011 Sep 21;133(37):14704-9
pubmed: 21800868
J Control Release. 2014 Sep 28;190:485-99
pubmed: 24984011
Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6595-E6602
pubmed: 28739953
ACS Nano. 2019 Feb 26;13(2):2501-2510
pubmed: 30668110
ACS Nano. 2012 Jun 26;6(6):5209-19
pubmed: 22548282
J Mater Chem B. 2018 Oct 7;6(37):5888-5895
pubmed: 30923616
Nanomedicine (Lond). 2016 Jan;11(1):81-100
pubmed: 26653875
Biomacromolecules. 2018 Mar 12;19(3):773-781
pubmed: 29328653
Science. 2013 Feb 22;339(6122):971-5
pubmed: 23430657
Nat Cell Biol. 2001 May;3(5):473-83
pubmed: 11331875
ACS Nano. 2019 Jan 22;13(1):236-247
pubmed: 30576113
NPG Asia Mater. 2017;9(4):e371
pubmed: 32218880
ACS Appl Mater Interfaces. 2018 Nov 21;10(46):39468-39477
pubmed: 30403330
Mol Pharm. 2018 Aug 6;15(8):2900-2909
pubmed: 29733602
ACS Nano. 2011 Jul 26;5(7):5729-45
pubmed: 21615170
Nat Rev Clin Oncol. 2018 Jun;15(6):366-381
pubmed: 29651130
Biomaterials. 2016 May;89:89-97
pubmed: 26950168
ACS Nano. 2015 Dec 22;9(12):12255-63
pubmed: 26496067
Nat Mater. 2013 Nov;12(11):958-62
pubmed: 24150413
Spectrochim Acta A Mol Biomol Spectrosc. 2019 Nov 5;222:117279
pubmed: 31234091
ACS Nano. 2013 Oct 22;7(10):8616-26
pubmed: 24047542
Int J Nanomedicine. 2007;2(4):715-33
pubmed: 18203438
Anal Bioanal Chem. 2011 Jan;399(1):3-27
pubmed: 20924568
J Gene Med. 2018 May;20(5):e3015
pubmed: 29575374
Adv Healthc Mater. 2015 Apr 22;4(6):874-82
pubmed: 25641794
Oncogenesis. 2018 Jan 24;7(1):10
pubmed: 29362402
J Control Release. 2017 Jun 10;255:258-269
pubmed: 28456679
Nanoscale. 2014 Jul 7;6(13):7124-41
pubmed: 24860847
ACS Nano. 2016 Mar 22;10(3):3453-60
pubmed: 26871955
Angew Chem Int Ed Engl. 2018 Mar 5;57(11):2909-2913
pubmed: 29359486
Mol Pharm. 2013 Jan 7;10(1):26-32
pubmed: 22905759
ACS Nano. 2014 Jun 24;8(6):6004-13
pubmed: 24806291
Trends Mol Med. 2010 Dec;16(12):574-83
pubmed: 20870460
ACS Nano. 2017 Sep 26;11(9):9249-9258
pubmed: 28858475
Nat Rev Clin Oncol. 2010 Nov;7(11):653-64
pubmed: 20838415
J Hazard Mater. 2013 Apr 15;250-251:167-74
pubmed: 23454454
Nano Lett. 2019 Mar 13;19(3):1467-1478
pubmed: 30730145
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2015 Sep-Oct;7(5):708-21
pubmed: 25683790
Biomater Sci. 2019 Aug 1;7(8):3138-3142
pubmed: 31257379
ACS Nano. 2013 Jun 25;7(6):4830-7
pubmed: 23718215
Mol Ther Methods Clin Dev. 2016 Apr 06;3:16018
pubmed: 27088104
ACS Nano. 2013 Aug 27;7(8):6988-96
pubmed: 23829542
ACS Nano. 2015 Sep 22;9(9):9134-47
pubmed: 26266824
J Mater Chem B. 2018 Apr 21;6(15):2204-2216
pubmed: 30294445
J Control Release. 2017 Dec 10;267:172-180
pubmed: 28821462
Nat Nanotechnol. 2018 Sep;13(9):777-785
pubmed: 30190620
PET Clin. 2016 Jul;11(3):203-7
pubmed: 27321025
Nanomedicine (Lond). 2014 Feb;9(2):221-35
pubmed: 23834501
Mol Pharm. 2016 Nov 7;13(11):3764-3772
pubmed: 27611245
J Mater Chem B. 2019 Feb 21;7(7):1056-1063
pubmed: 32254773
Nano Lett. 2018 Sep 12;18(9):5453-5460
pubmed: 30091612
Nat Nanotechnol. 2014 Apr;9(4):311-6
pubmed: 24633522
J Control Release. 2017 Aug 10;259:92-104
pubmed: 28189629
Nano Lett. 2017 Feb 8;17(2):862-869
pubmed: 28027646