Chronic hepatitis delta: A state-of-the-art review and new therapies.
Antiviral Agents
/ pharmacology
Coinfection
/ drug therapy
Drug Therapy, Combination
/ methods
Global Burden of Disease
Hepatitis B Surface Antigens
/ immunology
Hepatitis B virus
/ immunology
Hepatitis B, Chronic
/ drug therapy
Hepatitis D, Chronic
/ drug therapy
Hepatitis Delta Virus
/ immunology
Humans
Interferon-alpha
/ pharmacology
Lipopeptides
/ pharmacology
Organic Anion Transporters, Sodium-Dependent
/ antagonists & inhibitors
Piperidines
/ pharmacology
Pyridines
/ pharmacology
Randomized Controlled Trials as Topic
Review Literature as Topic
Superinfection
/ drug therapy
Symporters
/ antagonists & inhibitors
Therapies, Investigational
/ methods
Treatment Outcome
Virus Assembly
/ drug effects
Virus Internalization
/ drug effects
Epidemiology
Hepatitis delta
Treatment
Journal
World journal of gastroenterology
ISSN: 2219-2840
Titre abrégé: World J Gastroenterol
Pays: United States
ID NLM: 100883448
Informations de publication
Date de publication:
28 Aug 2019
28 Aug 2019
Historique:
received:
21
05
2019
revised:
03
07
2019
accepted:
19
07
2019
entrez:
19
9
2019
pubmed:
19
9
2019
medline:
15
2
2020
Statut:
ppublish
Résumé
Chronic delta hepatitis is the most severe form of viral hepatitis affecting nearly 65 million people worldwide. Individuals with this devastating illness are at higher risk for developing cirrhosis and hepatocellular carcinoma. Delta virus is a defective RNA virus that requires hepatitis B surface antigen for propagation in humans. Infection can occur in the form of a co-infection with hepatitis B, which can be self-limiting,
Identifiants
pubmed: 31528088
doi: 10.3748/wjg.v25.i32.4580
pmc: PMC6718034
doi:
Substances chimiques
Antiviral Agents
0
Hepatitis B Surface Antigens
0
Interferon-alpha
0
Lipopeptides
0
Organic Anion Transporters, Sodium-Dependent
0
Piperidines
0
Pyridines
0
Symporters
0
myrcludex-B
0
sodium-bile acid cotransporter
145420-23-1
lonafarnib
IOW153004F
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
4580-4597Déclaration de conflit d'intérêts
Conflict-of-interest statement: The authors have no conflict of interest to report.
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