A bioinspired, photostable UV-filter that protects mammalian cells against UV-induced cellular damage.

Animals Antioxidants / chemistry Cell Survival / drug effects DNA Damage Dimethylpolysiloxanes / chemistry Humans Mice NIH 3T3 Cells Oxazines / chemistry Proof of Concept Study Skin / cytology Sunscreening Agents / chemistry Ultraviolet Rays Xanthenes / chemistry

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
03 Oct 2019
Historique:
pubmed: 19 9 2019
medline: 2 11 2019
entrez: 19 9 2019
Statut: ppublish

Résumé

While commercially available suncare products are effective at absorbing ultraviolet (UV)-light, recent studies indicate systemic toxicities associated with many traditional chemical and physical UV-filters. We demonstrate the application of xanthommatin, a biochrome present in arthropods and cephalopods, as an alternative chemical UV-filter that is cytocompatible while maintaining its photostability and photoprotective properties.

Identifiants

DOI: 10.1039/c9cc06323d PMID: 31531454
pubmed: 31531454
doi: 10.1039/c9cc06323d
doi:

Substances chimiques

Antioxidants 0
Dimethylpolysiloxanes 0
Oxazines 0
Sunscreening Agents 0
Xanthenes 0
xanthommatin 521-58-4
baysilon 63148-62-9

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

12036-12039

Auteurs

Camille A Martin (CA)

Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA. l.deravi@northeastern.edu.
ORCID: 0000-0003-1147-4298

Mahboobeh Rezaeeyazdi (M)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.

Thibault Colombani (T)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.

Sean R Dinneen (SR)

Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA. l.deravi@northeastern.edu.
ORCID: 0000-0002-8119-9466

Amrita Kumar (A)

Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA. l.deravi@northeastern.edu.

Sidi A Bencherif (SA)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA and Department of Bioengineering, Northeastern University, Boston, MA 02115, USA and John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02128, USA.
ORCID: 0000-0002-7704-5608

Leila F Deravi (LF)

Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA. l.deravi@northeastern.edu.
ORCID: 0000-0003-3226-2470

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Antioxydants › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Phénomènes génétiques › Altération de l'ADN › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Siloxanes › Silicone › Polydiméthylsiloxanes › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Fibroblastes › Cellules 3T3 › Cellules NIH 3T3 › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Oxazines › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Disciplines des sciences naturelles › Science › Recherche › Étude de validation de principe › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Système tégumentaire › Peau › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Radioprotecteurs › Produits antisolaires › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Environnement et santé publique › Environnement › Concepts météorologiques › Atmosphère › Temps (météorologie) › Lumière du soleil › Rayons ultraviolets › A bioinspired, photostable UV-filter that...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérocycliques 3 noyaux › Xanthènes › A bioinspired, photostable UV-filter that...