Adult
Antineoplastic Combined Chemotherapy Protocols
/ therapeutic use
DNA-Binding Proteins
/ genetics
Hematopoietic Stem Cell Transplantation
Humans
Lymphoma, Mantle-Cell
/ diagnosis
Mutation
Neoplasm Proteins
/ genetics
Prognosis
Prospective Studies
Transplantation, Autologous
Tumor Suppressor Protein p53
/ genetics
Journal
Haematologica
ISSN: 1592-8721
Titre abrégé: Haematologica
Pays: Italy
ID NLM: 0417435
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
24
12
2018
accepted:
19
09
2019
pubmed:
21
9
2019
medline:
28
4
2021
entrez:
21
9
2019
Statut:
ppublish
Résumé
In recent years, the outcome of mantle cell lymphoma (MCL) has improved, especially in younger patients, receiving cytarabine-containing chemoimmunotherapy and autologous stem cell transplantation. Nevertheless, a proportion of MCL patients still experience early failure. To identify biomarkers anticipating failure of intensive chemotherapy in MCL, we performed target resequencing and DNA profiling of purified tumor samples collected from patients enrolled in the prospective
Identifiants
pubmed: 31537689
pii: haematol.2018.214056
doi: 10.3324/haematol.2018.214056
pmc: PMC7271566
doi:
Substances chimiques
DNA-Binding Proteins
0
KMT2D protein, human
0
Neoplasm Proteins
0
TP53 protein, human
0
Tumor Suppressor Protein p53
0
Banques de données
ClinicalTrials.gov
['NCT02354313']
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1604-1612Informations de copyright
Copyright© 2020 Ferrata Storti Foundation.
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