Postural Abnormalities in Parkinson's Disease: An Epidemiological and Clinical Multicenter Study.
Parkinson's disease
Pisa syndrome
anterocollis
camptocormia
postural abnormalities
Journal
Movement disorders clinical practice
ISSN: 2330-1619
Titre abrégé: Mov Disord Clin Pract
Pays: United States
ID NLM: 101630279
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
25
03
2019
revised:
01
06
2019
accepted:
12
06
2019
entrez:
21
9
2019
pubmed:
21
9
2019
medline:
21
9
2019
Statut:
epublish
Résumé
The overall frequency of postural abnormalities (PA) in Parkinson's disease (PD) is unknown. We evaluated the overall prevalence of PA and assessed the association with demographic and clinical variables. For this multicenter, cross-sectional study, consecutive PD outpatients attending 7 tertiary Italian centers were enrolled. Patients were evaluated and compared for the presence of isolated PA such as camptocormia, Pisa syndrome, and anterocollis and for combined forms (ie, camptocormia + Pisa syndrome) together with demographic and clinical variables. Of the total 811 PD patients enrolled, 174 (21.5%; 95% confidence interval [CI], 18.6%-24.3%) presented PA, 144 of which had isolated PA and 30 had combined PA. The prevalence of camptocormia was 11.2% (95% CI, 9%-13.3%), Pisa syndrome 8% (95% CI, 6.2%-9.9%), and anterocollis 6.5% (95% CI, 4.9%-8.3%). Patients with PA were more often male and older with longer disease duration, more advanced disease stage, more severe PD symptoms, a bradykinetic/rigid phenotype, and poorer quality of life. They were initially treated with l PA are frequent and disabling complications in PD, especially in the advanced disease stages.
Identifiants
pubmed: 31538092
doi: 10.1002/mdc3.12810
pii: MDC312810
pmc: PMC6749805
doi:
Types de publication
Journal Article
Langues
eng
Pagination
576-585Déclaration de conflit d'intérêts
Financial support for the study was provided by the Brain Research Foundation Verona O.N.L.U.S. All authors report no disclosures and no conflict of interests.
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