Polysomnography Parameters Assessing Gas Exchange Best Predict Postoperative Respiratory Complications Following Adenotonsillectomy in Children With Severe OSA.


Journal

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
ISSN: 1550-9397
Titre abrégé: J Clin Sleep Med
Pays: United States
ID NLM: 101231977

Informations de publication

Date de publication:
15 09 2019
Historique:
entrez: 21 9 2019
pubmed: 21 9 2019
medline: 18 11 2020
Statut: ppublish

Résumé

Adenotonsillectomy (AT) is the treatment of choice for obstructive sleep apnea (OSA) in children with adenotonsillar hypertrophy. Severe OSA, identified by the apnea-hypopnea index (AHI), is a risk factor for surgical complications and AHI thresholds are used by surgeons to decide elective postoperative hospital admissions. The objective of this study was to identify the prevalence of surgical complications of AT in children with severe OSA and determine their association with specific parameters of polysomnography (PSG). Retrospective evaluation of respiratory and nonrespiratory complications in children undergoing AT for severe OSA was performed. Events were then compared to several individual PSG indices. PSG indices included classic parameters such as AHI, and obstructive apnea indexes (OAI) as well as gas exchange parameters including the oxygen desaturation index (ODI), lowest oxyhemoglobin saturation (lowest SpO₂), peak end-tidal CO₂ (peak ETCO₂), the percentage of the total sleep time (%TST) with ETCO₂ > 50 mmHg (%TST ETCO₂ > 50 mmHg) and oxygen saturation < 90% (%TST O₂ < 90%). A total of 158 children were identified with severe OSA. Major respiratory complications occurred in 21.5% and were only associated with the ODI (P = .014), lowest SpO₂ (P = .001) and %TST O₂ < 90% (P < .001). Minor respiratory complications occurred in 19.6% and these were not associated with any PSG parameters. Major nonrespiratory complications occurred in 4.4% and also were not associated with any PSG parameters; however, minor nonrespiratory complications occurring in 37.3%, and were associated with %TST O₂ < 90% (P < 0.001). PSG measures of gas exchange are strongly associated with postoperative complications of AT and are better suited for postoperative planning than classic indices such as AHI. Molero-Ramirez H, Tamae Kakazu M, Baroody F, Bhattacharjee R. Polysomnography parameters assessing gas exchange best predict postoperative respiratory complications following adenotonsillectomy in children with severe OSA. J Clin Sleep Med. 2019;15(9):1251-1259.

Identifiants

pubmed: 31538596
doi: 10.5664/jcsm.7914
pmc: PMC6760392
doi:

Substances chimiques

Oxygen S88TT14065

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1251-1259

Informations de copyright

© 2019 American Academy of Sleep Medicine.

Références

Pediatr Pulmonol. 1988;4(3):139-43
pubmed: 2836784
Dev Sci. 2006 Jul;9(4):388-99
pubmed: 16764612
Otolaryngol Head Neck Surg. 2009 Jun;140(6):894-901
pubmed: 19467411
Pediatrics. 2008 May;121(5):e1208-14
pubmed: 18450864
Int J Pediatr Otorhinolaryngol. 2011 Nov;75(11):1385-90
pubmed: 21871668
Otolaryngol Head Neck Surg. 2014 Dec;151(6):1046-54
pubmed: 25301788
Pediatrics. 1998 Sep;102(3 Pt 1):616-20
pubmed: 9738185
Arch Otolaryngol Head Neck Surg. 1992 Sep;118(9):940-3
pubmed: 1503720
Pediatrics. 2015 Oct;136(4):702-18
pubmed: 26391937
Pediatrics. 1994 May;93(5):784-8
pubmed: 8165079
Arch Otolaryngol Head Neck Surg. 2011 Jan;137(1):15-8
pubmed: 21242540
Hypertension. 2008 Jan;51(1):84-91
pubmed: 18071053
Pediatr Pulmonol. 2005 Apr;39(4):332-8
pubmed: 15704184
Nat Sci Sleep. 2013 Sep 25;5:109-23
pubmed: 24109201
Otolaryngol Head Neck Surg. 2011 Jul;145(1 Suppl):S1-15
pubmed: 21676944
Semin Pediatr Neurol. 2008 Jun;15(2):100-6
pubmed: 18555196
Expert Rev Respir Med. 2011 Jun;5(3):425-40
pubmed: 21702663
Otolaryngol Head Neck Surg. 2010 Nov;143(5):680-4
pubmed: 20974339
Sleep Med Rev. 2008 Oct;12(5):339-46
pubmed: 18406637
Circulation. 2007 Nov 13;116(20):2307-14
pubmed: 17967978
Urology. 2005 Jul;66(1):194
pubmed: 15961142
Proc Am Thorac Soc. 2008 Feb 15;5(2):242-52
pubmed: 18250218
Am J Respir Crit Care Med. 2007 Jan 1;175(1):55-61
pubmed: 17038661
N Engl J Med. 2013 Jun 20;368(25):2366-76
pubmed: 23692173
Anesthesiology. 2006 Oct;105(4):665-9
pubmed: 17006062
Int J Pediatr Otorhinolaryngol. 2006 May;70(5):769-78
pubmed: 16460816
Am J Respir Crit Care Med. 2010 Sep 1;182(5):676-83
pubmed: 20448096
Int J Pediatr Otorhinolaryngol. 2015 Feb;79(2):240-5
pubmed: 25575425
Pediatrics. 2012 Sep;130(3):576-84
pubmed: 22926173

Auteurs

Helena Molero-Ramirez (H)

Deparment of Pediatrics, Division of Pediatric Pulmonology, University of Minnesota, Minneapolis, Minnesota.

Maximiliano Tamae Kakazu (M)

Spectrum Health-Michigan State University, Grand Rapids, Michigan.

Fuad Baroody (F)

Departments of Surgery, Section of Otolaryngology-Head and Neck Surgery, and Pediatrics, University of Chicago, Pritzker School of Medicine, Chicago, Illinois.

Rakesh Bhattacharjee (R)

Department of Pediatrics, Division of Respiratory Medicine, University of California-San Diego and Rady Children's Hospital of San Diego, San Diego, California.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH