Contributions of autism evaluation unit in the clinical diagnosis of autism spectrum disorders.
Adult
Autism Spectrum Disorder
/ complications
Autistic Disorder
/ diagnosis
Child
Child, Preschool
Comorbidity
Consanguinity
Diagnostic Techniques, Neurological
Electroencephalography
Epilepsy
/ complications
Female
Humans
Male
Neurologic Examination
/ methods
Psychology, Child
Psychometrics
/ methods
Retrospective Studies
Severity of Illness Index
Journal
La Tunisie medicale
ISSN: 2724-7031
Titre abrégé: Tunis Med
Pays: Tunisia
ID NLM: 0413766
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
entrez:
21
9
2019
pubmed:
21
9
2019
medline:
25
3
2020
Statut:
ppublish
Résumé
Based on the recognized principles of assessment of autistic disorders, the child and adolescent psychiatry department in Razi Hospital developed, in coordination with the department of neurology of Razi Hospital and the department of genetics of Charles Nicolle's Hospital an assessment unit for autism spectrum disorders. To describe the clinical characteristics in terms of severity and comorbidities of children assessed for autism spectrum disorders. We compiled data about clinical examination of autistic symptoms using the Autism Diagnostic Interview Revised (ADI-R) and the Childhood autism Rating Scale (CARS). Each child developmental age was determined using the Psycho Educative Profile (PEP-R). Neurological examination completed with electroencephalography and genetics testing (caryoptype and X fragile) were performed. Fifty-two children were included in our study. The mean age was 6.6 years with a sex ratio of 6.5. The severity of the clinical presentations was assessed through the following score means: CARS 35, ADI-B: 20, ADI-C: 13, ADI-D: 7, functional developmental age: 2.4 years. Comorbidity with epilepsy was present in 7% of cases and an intellectual disability was found in 80% of them. Genetic tests were normal. Our results will be discussed in the light of international recommendations.
Sections du résumé
BACKGROUND
BACKGROUND
Based on the recognized principles of assessment of autistic disorders, the child and adolescent psychiatry department in Razi Hospital developed, in coordination with the department of neurology of Razi Hospital and the department of genetics of Charles Nicolle's Hospital an assessment unit for autism spectrum disorders.
OBJECTIVE
OBJECTIVE
To describe the clinical characteristics in terms of severity and comorbidities of children assessed for autism spectrum disorders.
METHODS
METHODS
We compiled data about clinical examination of autistic symptoms using the Autism Diagnostic Interview Revised (ADI-R) and the Childhood autism Rating Scale (CARS). Each child developmental age was determined using the Psycho Educative Profile (PEP-R). Neurological examination completed with electroencephalography and genetics testing (caryoptype and X fragile) were performed.
RESULTS
RESULTS
Fifty-two children were included in our study. The mean age was 6.6 years with a sex ratio of 6.5. The severity of the clinical presentations was assessed through the following score means: CARS 35, ADI-B: 20, ADI-C: 13, ADI-D: 7, functional developmental age: 2.4 years. Comorbidity with epilepsy was present in 7% of cases and an intellectual disability was found in 80% of them. Genetic tests were normal.
CONCLUSION
CONCLUSIONS
Our results will be discussed in the light of international recommendations.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM