Endogenous nicotinamide riboside metabolism protects against diet-induced liver damage.
Animals
Blood Glucose
DNA Damage
Diet, High-Fat
/ adverse effects
Disease Models, Animal
Gene Knockout Techniques
Genetic Predisposition to Disease
/ genetics
Glucose Intolerance
Hepatocytes
/ metabolism
Insulin Resistance
Lipid Metabolism
Liver
/ metabolism
Liver Diseases
/ genetics
Male
Metabolic Syndrome
/ genetics
Mice
Mice, Inbred C57BL
Mice, Knockout
NAD
/ metabolism
Niacinamide
/ analogs & derivatives
Phosphotransferases (Alcohol Group Acceptor)
/ genetics
Protective Agents
/ metabolism
Pyridinium Compounds
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
20 09 2019
20 09 2019
Historique:
received:
10
10
2018
accepted:
30
08
2019
entrez:
22
9
2019
pubmed:
22
9
2019
medline:
7
1
2020
Statut:
epublish
Résumé
Supplementation with the NAD
Identifiants
pubmed: 31541116
doi: 10.1038/s41467-019-12262-x
pii: 10.1038/s41467-019-12262-x
pmc: PMC6754455
doi:
Substances chimiques
Blood Glucose
0
Protective Agents
0
Pyridinium Compounds
0
nicotinamide-beta-riboside
0I8H2M0L7N
NAD
0U46U6E8UK
Niacinamide
25X51I8RD4
Phosphotransferases (Alcohol Group Acceptor)
EC 2.7.1.-
Nmrk1 protein, mouse
EC 2.7.1.22
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4291Références
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