Lichen Planus and Metabolic Syndrome: Is There a Relation?
Correlation
lichen planus
metabolic syndrome
Journal
Indian dermatology online journal
ISSN: 2229-5178
Titre abrégé: Indian Dermatol Online J
Pays: India
ID NLM: 101586880
Informations de publication
Date de publication:
Historique:
entrez:
24
9
2019
pubmed:
24
9
2019
medline:
24
9
2019
Statut:
epublish
Résumé
Recent data suggests association of lichen planus (LP) with various systemic disorders. Relationship between LP and metabolic syndrome (MS) is not yet taken into account. MS has been associated with increased risk of cardiovascular diseases. Hence, earlier detection and treatment could potentially decrease mortality and improve the quality of life in these patients. To find out the association of LP with MS. About 100 LP patients and 50 healthy adults were investigated for fasting blood glucose (FBS) and lipid profile. MS was diagnosed as per National Cholesterol Education Program's Adult Treatment Panel III guidelines. Serum cholesterol, triglycerides, low density lipoprotein (LDL-C), and very low density lipoprotein (VLDL-C) values were significantly increased in cases as compared to controls ( As the cases and controls are included from a local area, the result may differ from other parts of the world. Diabetes mellitus, dyslipidemia, and MS are seen more commonly in LP patients.
Sections du résumé
BACKGROUND
BACKGROUND
Recent data suggests association of lichen planus (LP) with various systemic disorders. Relationship between LP and metabolic syndrome (MS) is not yet taken into account. MS has been associated with increased risk of cardiovascular diseases. Hence, earlier detection and treatment could potentially decrease mortality and improve the quality of life in these patients.
OBJECTIVES
OBJECTIVE
To find out the association of LP with MS.
MATERIALS AND METHODS
METHODS
About 100 LP patients and 50 healthy adults were investigated for fasting blood glucose (FBS) and lipid profile. MS was diagnosed as per National Cholesterol Education Program's Adult Treatment Panel III guidelines.
RESULTS
RESULTS
Serum cholesterol, triglycerides, low density lipoprotein (LDL-C), and very low density lipoprotein (VLDL-C) values were significantly increased in cases as compared to controls (
LIMITATIONS
CONCLUSIONS
As the cases and controls are included from a local area, the result may differ from other parts of the world.
CONCLUSION
CONCLUSIONS
Diabetes mellitus, dyslipidemia, and MS are seen more commonly in LP patients.
Identifiants
pubmed: 31544075
doi: 10.4103/idoj.IDOJ_499_18
pii: IDOJ-10-555
pmc: PMC6743384
doi:
Types de publication
Journal Article
Langues
eng
Pagination
555-559Déclaration de conflit d'intérêts
There are no conflicts of interest.
Références
J Eur Acad Dermatol Venereol. 2011 Dec;25(12):1398-401
pubmed: 21348899
Indian J Endocrinol Metab. 2014 May;18(3):274-82
pubmed: 24944918
Br J Dermatol. 2009 Sep;161(3):626-9
pubmed: 19438850
Med J Islam Repub Iran. 2012 Feb;26(1):22-6
pubmed: 23482842
J Dermatol. 2004 Apr;31(4):293-8
pubmed: 15187324
Am J Health Syst Pharm. 2003 Jul 1;60(13 Suppl 2):S3-8; quiz S25
pubmed: 12901024
J Eur Acad Dermatol Venereol. 2010 Oct;24(10):1144-50
pubmed: 20202047
Circ Cardiovasc Qual Outcomes. 2012 May;5(3):343-51
pubmed: 22550130
Am J Med. 2011 Jun;124(6):543-8
pubmed: 21605731
Oral Dis. 2010 Oct;16(7):601-12
pubmed: 20412447
Am Fam Physician. 2011 Jul 1;84(1):53-60
pubmed: 21766756
Indian J Dent Res. 1992 Jul-Sep;3(3):84-9
pubmed: 1343961
Med Oral. 2002 Mar-Apr;7(2):121-9
pubmed: 11887019
BMJ. 1990 Jan 27;300(6719):227-30
pubmed: 2106930
Clin Exp Dermatol. 2010 Apr;35(3):257-62
pubmed: 19874373
Hellenic J Cardiol. 2014 Mar-Apr;55(2):92-100
pubmed: 24681786
Am J Clin Dermatol. 2012 Dec 1;13(6):399-404
pubmed: 22924867
Psychosom Med. 2004 Jul-Aug;66(4):620-4
pubmed: 15272112
Indian J Dermatol. 2012 Mar;57(2):107-9
pubmed: 22615505
Dermatology. 2008;216(2):152-5
pubmed: 18216477
Circulation. 2005 Oct 25;112(17):2735-52
pubmed: 16157765
Bull Group Int Rech Sci Stomatol Odontol. 1993 Mar-Jun;36(1-2):3-6
pubmed: 8318821