Chinese nonmedicinal herbal diet and risk of nasopharyngeal carcinoma: A population-based case-control study.
case-control studies
herbal diet
herbs
nasopharyngeal carcinoma
Journal
Cancer
ISSN: 1097-0142
Titre abrégé: Cancer
Pays: United States
ID NLM: 0374236
Informations de publication
Date de publication:
15 12 2019
15 12 2019
Historique:
received:
15
04
2019
revised:
06
07
2019
accepted:
11
07
2019
pubmed:
24
9
2019
medline:
27
5
2020
entrez:
24
9
2019
Statut:
ppublish
Résumé
An association between a nonmedicinal herbal diet and nasopharyngeal carcinoma (NPC) has often been hypothesized but never thoroughly investigated. This study enrolled a total of 2469 patients with incident NPC and 2559 population controls from parts of Guangdong and Guangxi Provinces in southern China between 2010 and 2014. Questionnaire information was collected on the intake of traditional herbal tea and herbal soup as well as the specific herbal plants used in soups and other potentially confounding lifestyle factors. Multivariate logistic regression models were used to estimate odds ratios (ORs) with 95% confidence intervals (CIs) for the NPC risk in association with herbal tea and soup intake. Ever consumption of herbal tea was not associated with NPC risk (OR, 1.03; 95% CI, 0.91-1.17). An inverse association was observed for NPC among ever drinkers of herbal soup (OR, 0.78; 95% CI, 0.67-0.90) but without any monotonic trend with an increasing frequency or duration of herbal soup consumption. Inverse associations with NPC risk were detected with 9 herbal plants used in herbal soup, including Ziziphus jujuba, Fructus lycii, Codonopsis pilosula, Astragalus membranaceus, Semen coicis, Smilax glabra, Phaseolus calcaratus, Morinda officinalis, and Atractylodes macrocephala (OR range, 0.31-0.79). Consuming herbal soups including specific plants, but not herbal tea, was inversely associated with NPC. If replicated, these results might provide potential for NPC prevention in endemic areas.
Sections du résumé
BACKGROUND
An association between a nonmedicinal herbal diet and nasopharyngeal carcinoma (NPC) has often been hypothesized but never thoroughly investigated.
METHODS
This study enrolled a total of 2469 patients with incident NPC and 2559 population controls from parts of Guangdong and Guangxi Provinces in southern China between 2010 and 2014. Questionnaire information was collected on the intake of traditional herbal tea and herbal soup as well as the specific herbal plants used in soups and other potentially confounding lifestyle factors. Multivariate logistic regression models were used to estimate odds ratios (ORs) with 95% confidence intervals (CIs) for the NPC risk in association with herbal tea and soup intake.
RESULTS
Ever consumption of herbal tea was not associated with NPC risk (OR, 1.03; 95% CI, 0.91-1.17). An inverse association was observed for NPC among ever drinkers of herbal soup (OR, 0.78; 95% CI, 0.67-0.90) but without any monotonic trend with an increasing frequency or duration of herbal soup consumption. Inverse associations with NPC risk were detected with 9 herbal plants used in herbal soup, including Ziziphus jujuba, Fructus lycii, Codonopsis pilosula, Astragalus membranaceus, Semen coicis, Smilax glabra, Phaseolus calcaratus, Morinda officinalis, and Atractylodes macrocephala (OR range, 0.31-0.79).
CONCLUSIONS
Consuming herbal soups including specific plants, but not herbal tea, was inversely associated with NPC. If replicated, these results might provide potential for NPC prevention in endemic areas.
Identifiants
pubmed: 31544233
doi: 10.1002/cncr.32458
pmc: PMC6891117
mid: NIHMS1043820
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4462-4470Subventions
Organisme : Swedish Research Council
ID : 2015-02625, 2015-06268, 2017-05814
Pays : International
Organisme : The National Key Research and Development Program of China
ID : 2017YFC0907100
Pays : International
Organisme : National Key Research and Development Program of China
ID : 2017YFC0907100
Pays : International
Organisme : Karolinska Institutet Distinguished Professor Award
ID : Dnr: 2368/10-221
Pays : International
Organisme : Karolinska Institute
ID : Dnr 2368/10-221
Pays : International
Organisme : National Natural Science Foundation of China
ID : 81872700
Pays : International
Organisme : NCI NIH HHS
ID : R01 CA115873
Pays : United States
Organisme : Guangxi Natural Science Foundation
ID : 2013GXNSFGA 019002
Pays : International
Organisme : New Century Excellent Talents in University
ID : NCET-12-0654
Pays : International
Organisme : Natural Science Foundation of Guangxi Province
ID : 2013GXNSFGA 019002
Pays : International
Organisme : Swedish Research Council
ID : 2017-05814
Pays : International
Organisme : Natural Science Foundation of China
ID : 81872700
Pays : International
Organisme : Swedish Research Council
ID : 2015-02625
Pays : International
Organisme : National Basic Research Program of China
ID : 2011CB504300
Pays : International
Organisme : Swedish Research Council
ID : 2015-06268
Pays : International
Organisme : Program for New Century Excellent Talents in University
ID : NCET-12-0654
Pays : International
Informations de copyright
© 2019 American Cancer Society.
Références
Br J Cancer. 1994 Mar;69(3):508-14
pubmed: 8123482
Int J Cancer. 1989 Jun 15;43(6):1077-82
pubmed: 2732001
Front Immunol. 2017 Aug 02;8:905
pubmed: 28824631
Br J Nutr. 2012 Mar;107(5):712-8
pubmed: 21864416
Nutr Cancer. 2016 Oct;68(7):1123-30
pubmed: 27564524
Thorac Cancer. 2018 May;9(5):630-639
pubmed: 29577649
J Ethnobiol Ethnomed. 2018 Jan 15;14(1):4
pubmed: 29334976
Pharm Biol. 2015 Apr;53(4):512-7
pubmed: 25327442
J Natl Cancer Inst. 1973 Nov;51(5):1403-8
pubmed: 4762926
J Pharm Pharmacol. 2005 May;57(5):607-15
pubmed: 15901350
Chin J Cancer. 2015 May 14;34(8):350-7
pubmed: 26058679
Cancer Epidemiol Biomarkers Prev. 2016 Aug;25(8):1201-7
pubmed: 27197279
Int J Biol Macromol. 2013 Nov;62:287-90
pubmed: 24060282
Am J Chin Med. 2016;44(3):463-88
pubmed: 27109156
Philos Trans R Soc Lond B Biol Sci. 2017 Oct 19;372(1732):
pubmed: 28893937
Integr Cancer Ther. 2018 Sep;17(3):860-866
pubmed: 29355051
Chem Biodivers. 2017 Nov;14(11):null
pubmed: 28795782
PLoS One. 2011 Apr 22;6(4):e19100
pubmed: 21544243
BMC Cancer. 2010 Aug 20;10:446
pubmed: 20727127
Oncotarget. 2017 Jul 29;8(50):87073-87085
pubmed: 29152064
Int J Cancer. 1993 Nov 11;55(5):722-7
pubmed: 7503957
BMC Cancer. 2006 Jul 06;6:178
pubmed: 16822324
Sci Transl Med. 2013 Aug 7;5(197):197ra102
pubmed: 23926200
Int J Mol Sci. 2017 Jan 19;18(1):
pubmed: 28106828
Biomed Environ Sci. 1994 Mar;7(1):50-5
pubmed: 8024719
Asian Pac J Cancer Prev. ;18(2):399-403
pubmed: 28345821
Semin Cancer Biol. 2012 Apr;22(2):117-26
pubmed: 22311401
J Natl Cancer Inst. 2010 Feb 3;102(3):179-86
pubmed: 20026811
Int J Cancer. 2009 Jun 15;124(12):2942-7
pubmed: 19296536
Cancers (Basel). 2018 Apr 17;10(4):null
pubmed: 29673164
Food Chem Toxicol. 2013 Mar;53:263-71
pubmed: 23261679
Am J Epidemiol. 2018 Oct 1;187(10):2117-2125
pubmed: 29701753
Int J Cancer. 2018 Oct 1;143(7):1578-1587
pubmed: 29667191
Int J Pharm. 2016 Apr 30;503(1-2):90-101
pubmed: 26947738
Int J Biol Macromol. 2018 Mar;108:541-549
pubmed: 29233708
Phytother Res. 2014 Oct;28(10):1527-32
pubmed: 24806434
Int J Cancer. 2007 Oct 1;121(7):1550-5
pubmed: 17582611
Cancer Res. 1992 Jun 1;52(11):3048-51
pubmed: 1317256
Molecules. 2013 Oct 29;18(11):13357-68
pubmed: 24172243
Evid Based Complement Alternat Med. 2014;2014:985176
pubmed: 24696703
Evid Based Complement Alternat Med. 2018 Jan 28;2018:2305683
pubmed: 29619065
J Ethnopharmacol. 2017 Jun 9;205:195-206
pubmed: 28249822
Cancer Commun (Lond). 2018 Apr 3;38(1):7
pubmed: 29764502
N Engl J Med. 2001 Dec 27;345(26):1877-82
pubmed: 11756578
Carbohydr Polym. 2017 Jan 20;156:390-402
pubmed: 27842838
PLoS One. 2015 Mar 31;10(3):e0122374
pubmed: 25825910