Choosing an Optimal Sample Preparation in

AMOPLS design of experiments high resolution mass spectrometry hydrophilic interaction liquid chromatography ion mobility spectrometry metabolomics sample preparation

Journal

Metabolites
ISSN: 2218-1989
Titre abrégé: Metabolites
Pays: Switzerland
ID NLM: 101578790

Informations de publication

Date de publication:
20 Sep 2019
Historique:
received: 27 08 2019
revised: 13 09 2019
accepted: 17 09 2019
entrez: 25 9 2019
pubmed: 25 9 2019
medline: 25 9 2019
Statut: epublish

Résumé

Untargeted metabolomics aims to provide a global picture of the metabolites present in the system under study. To this end, making a careful choice of sample preparation is mandatory to obtain reliable and reproducible biological information. In this study, eight different sample preparation techniques were evaluated using

Identifiants

pubmed: 31547088
pii: metabo9100193
doi: 10.3390/metabo9100193
pmc: PMC6836107
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Swiss National Science Foundation
ID : 31003A_166658
Pays : Switzerland
Organisme : Swiss Centre for Applied Human Toxicology
ID : Program 2017-2020 (Core Project 3: Neurotoxicity)

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Auteurs

Julian Pezzatti (J)

Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. julian.pezzatti@unige.ch.

Matthieu Bergé (M)

Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, University Medical Centre, 1206 Geneva, Switzerland. matthieu.berge@unige.ch.

Julien Boccard (J)

Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. julien.boccard@unige.ch.
Swiss Centre for Applied Human Toxicology, 4055 Basel, Switzerland. julien.boccard@unige.ch.

Santiago Codesido (S)

Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. santiago.codesido@unige.ch.

Yoric Gagnebin (Y)

Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. yoric.gagnebin@unige.ch.

Patrick H Viollier (P)

Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, University Medical Centre, 1206 Geneva, Switzerland. patrick.viollier@unige.ch.

Víctor González-Ruiz (V)

Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. victor.gonzalez@unige.ch.
Swiss Centre for Applied Human Toxicology, 4055 Basel, Switzerland. victor.gonzalez@unige.ch.

Serge Rudaz (S)

Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University Medical Centre, 1206 Geneva, Switzerland. serge.rudaz@unige.ch.
Swiss Centre for Applied Human Toxicology, 4055 Basel, Switzerland. serge.rudaz@unige.ch.

Classifications MeSH