Impact of Moderate Sodium Restriction and Hydrochlorothiazide on Iodine Excretion in Diabetic Kidney Disease: Data from a Randomized Cross-Over Trial.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
12 Sep 2019
Historique:
received: 11 06 2019
revised: 14 08 2019
accepted: 10 09 2019
entrez: 25 9 2019
pubmed: 25 9 2019
medline: 4 3 2020
Statut: epublish

Résumé

Sodium restriction may potentially reduce iodine intake. This study aimed to determine the effect of sodium restriction (dietary counseling) on 24-h urinary iodine excretion. Diuretics provide an alternative to sodium restriction and are frequently added to sodium restriction, so the effects of hydrochlorothiazide (50 mg daily) and combined therapy were also studied. We performed a post-hoc analysis of a Dutch multi-center, randomized cross-over trial in 45 patients with diabetic kidney disease with a mean age of 65 ± 9 years, mean eGFR of 65 ± 27 mL/min/1.73 m

Identifiants

pubmed: 31547438
pii: nu11092204
doi: 10.3390/nu11092204
pmc: PMC6770176
pii:
doi:

Substances chimiques

Sodium, Dietary 0
Hydrochlorothiazide 0J48LPH2TH
Iodine 9679TC07X4
Sodium 9NEZ333N27

Types de publication

Journal Article Multicenter Study Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

S Heleen Binnenmars (SH)

Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. s.h.binnenmars@umcg.nl.

Eva Corpeleijn (E)

Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. e.corpeleijn@umcg.nl.

Arjan J Kwakernaak (AJ)

Department of Internal Medicine, Division of Nephrology, Amsterdam University Medical Center, University of Amsterdam, 1100 DD Amsterdam, The Netherlands. a.j.kwakernaak@hotmail.com.

Daan J Touw (DJ)

Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. d.j.touw@umcg.nl.

Ido P Kema (IP)

Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. i.p.kema@umcg.nl.

Gozewijn D Laverman (GD)

Department of Internal Medicine, Division of Nephrology, ZGT Hospital, 7600 SZ Almelo/Hengelo, The Netherlands. g.laverman@zgt.nl.

Stephan J L Bakker (SJL)

Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. s.j.l.bakker@umcg.nl.

Gerjan Navis (G)

Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. g.j.navis@umcg.nl.

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