Vδ2 T-Cells Kill ZIKV-Infected Cells by NKG2D-Mediated Cytotoxicity.
NKG2D
Vδ2 T-cells
ZIKV
antiviral activity
cytotoxicity
innate immunity
perforin
Journal
Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893
Informations de publication
Date de publication:
12 Sep 2019
12 Sep 2019
Historique:
received:
19
07
2019
revised:
05
09
2019
accepted:
10
09
2019
entrez:
25
9
2019
pubmed:
25
9
2019
medline:
25
9
2019
Statut:
epublish
Résumé
An expansion of effector/activated Vδ2 T-cells was recently described in acute Zika virus (ZIKV)-infected patients, but their role in the protective immune response was not clarified. The aim of this study was to define the antiviral activity of Vδ2 T-cells against ZIKV-infected cells. The Vδ2 T-cells expansion and their cytotoxic activity against ZIKV-infected cells were tested
Identifiants
pubmed: 31547470
pii: microorganisms7090350
doi: 10.3390/microorganisms7090350
pmc: PMC6781265
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Ministero della Salute
ID : RF-2016-02364155
Organisme : Ministero della Salute
ID : RF-2016-02363642
Organisme : Ministero della Salute
ID : GR-2016-02362110
Organisme : Ministero della Salute
ID : Ricerca Corrente Linea 1
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