Antibacterial and antibiofilm properties of traditional medicinal plant from Sheikh Buddin range.


Journal

Pakistan journal of pharmaceutical sciences
ISSN: 1011-601X
Titre abrégé: Pak J Pharm Sci
Pays: Pakistan
ID NLM: 9426356

Informations de publication

Date de publication:
May 2019
Historique:
entrez: 26 9 2019
pubmed: 26 9 2019
medline: 13 2 2020
Statut: ppublish

Résumé

During current project, antibacterial and antibiofilm properties of traditional medicinal plant Ziziphus nummularia leaf extract and various fractions was investigated. The plant leaves were dried and extracted using 90% methanol followed by sequential fractionation using liquid-liquid fractionation. The fractions of a diverse polarity including chloroform, n-hexane, methanol and ethyl acetate and aqueous extracts were obtained that was further analysed by using HPLC. The phytochemical screening indicated presence of saponins, triterpenes and flavonoids. During DPPH assay, the methanolic fraction presented highest activity (IC

Identifiants

pubmed: 31551209

Substances chimiques

Anti-Bacterial Agents 0
Antioxidants 0
Flavonoids 0
Phenols 0
Plant Extracts 0
Saponins 0
Chloroform 7V31YC746X
Methanol Y4S76JWI15

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1313-1319

Auteurs

Aman Ullah (A)

Department of Pharmaceutical chemistry, Faculty of Pharmacy, Gomal University D.I. Khan, KPK, Pakistan.

Ghulam Mustafa (G)

Department of Pharmaceutical chemistry, Faculty of Pharmacy, Gomal University D.I. Khan, KPK, Pakistan.

Muhammad Hanif (M)

Gomal centre of Biochemistry and Biotechnology (GCBB), Gomal University D.I. Khan, KPK, Pakistan.

Muhammad Mohibullah (M)

Faculty of Agriculture, Gomal University, KPK, Pakistan.

Sattar Bakhsh (S)

Department of Pharmaceutics, Faculty of Pharmacy, Gomal University D.I. Khan, KPK, Pakistan.

Sheikh Abdur Rashid (SA)

Department of Pharmaceutics, Faculty of Pharmacy, Gomal University D.I. Khan, KPK, Pakistan.

Ali Zaman (A)

Institute of Microbiology, Gomal University, D.I. Khan, KPK, Pakistan.

Fazal Rehman (F)

Department of Pharmaceutical chemistry, Faculty of Pharmacy, Gomal University D.I. Khan, KPK, Pakistan.

Barkat Ali Khan (BA)

Department of Pharmaceutics, Faculty of Pharmacy, Gomal University D.I. Khan, KPK, Pakistan.

Adnan Amin (A)

NPRL, Department of Pharmacognosy, Faculty of Pharmacy, Gomal University D.I. Khan, KPK, Pakistan.

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Classifications MeSH