Perspective: Of Mice and Men - How Widespread Is Adult Neurogenesis?

adult neurogenesis hippocampus human neurogenesis neural stem/ progenitor cells neuroscience

Journal

Frontiers in neuroscience
ISSN: 1662-4548
Titre abrégé: Front Neurosci
Pays: Switzerland
ID NLM: 101478481

Informations de publication

Date de publication:
2019
Historique:
received: 09 05 2019
accepted: 16 08 2019
entrez: 27 9 2019
pubmed: 27 9 2019
medline: 27 9 2019
Statut: epublish

Résumé

These are exciting times for research on adult hippocampal neurogenesis (AHN). Debate and controversy regarding the existence of generation of new neurons in the adult, and even diseased human brain flourishes as articles against and in favor accumulate. Adult neurogenesis in the human brain is a phenomenon that does not share the qualities of quantum mechanics. The scientific community should agree that human AHN exists or does not, but not both at the same time. In this commentary, we discuss the latest research articles about hAHN and what their findings imply for the neurogenesis field.

Identifiants

pubmed: 31555083
doi: 10.3389/fnins.2019.00923
pmc: PMC6727861
doi:

Types de publication

Journal Article

Langues

eng

Pagination

923

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Auteurs

David Petrik (D)

School of Biosciences, Cardiff University, Cardiff, United Kingdom.
Institute of Stem Cell Research, Helmholtz Zentrum München, Munich, Germany.
Department of Physiological Genomics, Ludwig Maximilian University of Munich, Munich, Germany.

Juan M Encinas (JM)

Laboratory of Neural Stem Cells and Neurogenesis, Achucarro Basque Center for Neuroscience, Leioa, Spain.
IKERBASQUE, The Basque Foundation for Science, Bilbao, Spain.
Department of Neurosciences, University of the Basque Country (UPV/EHU), Leioa, Spain.

Classifications MeSH