Effect of Environment on the Evolutionary Trajectories and Growth Characteristics of Antibiotic-Resistant

antibiotic resistance biological cost evolution fitness urethral organoid urine

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2019
Historique:
received: 01 05 2019
accepted: 15 08 2019
entrez: 27 9 2019
pubmed: 27 9 2019
medline: 27 9 2019
Statut: epublish

Résumé

The fitness cost to bacteria of acquisition of resistance determinants is critically under-investigated, and the identification and exploitation of these fitness costs may lead to novel therapeutic strategies that prevent the emergence of antimicrobial resistance. Here we used

Identifiants

pubmed: 31555237
doi: 10.3389/fmicb.2019.02001
pmc: PMC6722461
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2001

Subventions

Organisme : Medical Research Council
ID : MR/R015074/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S004793/1
Pays : United Kingdom

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Auteurs

Alasdair T M Hubbard (ATM)

Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Nazila V Jafari (NV)

Centre for Urological Biology, Department of Renal Medicine, University College London, London, United Kingdom.

Nicholas Feasey (N)

Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Malawi-Liverpool-Wellcome Trust Clinical Research Programme, University of Malawi, College of Medicine, Blantyre, Malawi.

Jennifer L Rohn (JL)

Centre for Urological Biology, Department of Renal Medicine, University College London, London, United Kingdom.

Adam P Roberts (AP)

Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Classifications MeSH