The Potential Applications of Hyaluronic Acid Hydrogels in Biomedicine.


Journal

Drug research
ISSN: 2194-9387
Titre abrégé: Drug Res (Stuttg)
Pays: Germany
ID NLM: 101602406

Informations de publication

Date de publication:
Jan 2020
Historique:
pubmed: 27 9 2019
medline: 29 7 2020
entrez: 27 9 2019
Statut: ppublish

Résumé

Hyaluronic acid (HA) is widely used in the biomedicine due to its biocompatibility, biodegradability, and nontoxic properties. It is crucial for cell signaling role during morphogenesis, inflammation, and wound repair. After hydrogel formation, HA easily is converted to elastic sheets in order to use in preclinical and clinical applications. In addition, HA-derived hydrogels are easily used as vectors for cell and medication in tissue repairing and regenerative medicine. Moreover, in comparison with other polymers, HA -based hydrogels play a key role in in cellular behavior, including stem cell differentiation. The current paper reviews both basic concepts and recent advances in the development of HA-based hydrogels for biomedical applications.

Identifiants

pubmed: 31556074
doi: 10.1055/a-0991-7585
doi:

Substances chimiques

Biocompatible Materials 0
Hydrogels 0
Hyaluronic Acid 9004-61-9

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

6-11

Informations de copyright

© Georg Thieme Verlag KG Stuttgart · New York.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest associated with this work.

Auteurs

Elham Ahmadian (E)

Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Students' Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

Solmaz Maleki Dizaj (SM)

Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Aziz Eftekhari (A)

Maragheh University of Medical Sciences, Maragheh, Iran.

Elaheh Dalir (E)

Research Center for Pharmaceutical Nanotechnology, Biomedicine Institue, Tabriz University of Medical Sciences, Tabriz, Iran.

Parviz Vahedi (P)

Maragheh University of Medical Sciences, Maragheh, Iran.

Amir Hasanzadeh (A)

Maragheh University of Medical Sciences, Maragheh, Iran.

Mohammad Samiei (M)

Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

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Classifications MeSH