Recent developments and highlights in drug hypersensitivity.


Journal

Allergy
ISSN: 1398-9995
Titre abrégé: Allergy
Pays: Denmark
ID NLM: 7804028

Informations de publication

Date de publication:
12 2019
Historique:
received: 14 06 2019
revised: 18 09 2019
accepted: 19 09 2019
pubmed: 27 9 2019
medline: 10 9 2020
entrez: 27 9 2019
Statut: ppublish

Résumé

Drug hypersensitivity reactions (DHRs) are nowadays the third cause of allergy after rhinitis and asthma with a significant increase in prevalence in both adults and paediatric population with new drugs included as culprit. For this, DHRs represent not only a health problem but also a significant financial burden for affected individuals and health systems. Mislabelling DHRs is showing to be a relevant problem for both, false label of drug allergic and false label of nonallergic. All this reinforces the need to improve accurate diagnostic approaches that allow an appropriate management. Moreover, there is a need for training both, nonallergist stakeholders and patients to improve the reaction identification and therefore decrease the mislabelling. The use of allergy cards has shown to be relevant to avoid the induction of DHRs due to the prescription of wrong medication. Recent developments over the last 2 years and highlights about risk factors, diagnostic approaches, mechanisms involved as well as prevention actions, and management have been reviewed. In these papers, it has been outlined the need for correct diagnosis and de-labelling of patients previously false-reported as allergic, which will improve the management and treatment of patients with DHRs.

Identifiants

pubmed: 31557314
doi: 10.1111/all.14061
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2368-2381

Subventions

Organisme : Consejería de Salud, Junta de Andalucía
ID : C-0004-2016C
Pays : International
Organisme : Consejería de Salud, Junta de Andalucía
ID : PI-0241-2016; PE-0172-2018
Pays : International
Organisme : Instituto de Salud Carlos III
ID : PI15/01206
Pays : International
Organisme : Instituto de Salud Carlos III
ID : PI18/00095
Pays : International
Organisme : Instituto de Salud Carlos III
ID : RD16/0006/0001
Pays : International
Organisme : Instituto de Salud Carlos III
ID : RD16/0006/0019; CP15/00103; PI17/01237
Pays : International
Organisme : Secretaría de Estado de Investigación, Desarrollo e Innovación
ID : RYC-2013-13138
Pays : International

Informations de copyright

© 2019 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

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Auteurs

Cristobalina Mayorga (C)

Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA-ARADyAL, Málaga, Spain.
Allergy Unit, Hospital Regional Universitario de Málaga-ARADyAL, Málaga, Spain.
Andalusian Center for Nanomedicine and Biotechnology-BIONAND, Málaga, Spain.

Tahia D Fernandez (TD)

Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA-ARADyAL, Málaga, Spain.

Maria Isabel Montañez (MI)

Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA-ARADyAL, Málaga, Spain.
Andalusian Center for Nanomedicine and Biotechnology-BIONAND, Málaga, Spain.

Esther Moreno (E)

Allergy Unit, Hospital Universitario de Salamanca-ARADyAL, IBSAL, Salamanca, Spain.

María José Torres (MJ)

Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA-ARADyAL, Málaga, Spain.
Allergy Unit, Hospital Regional Universitario de Málaga-ARADyAL, Málaga, Spain.
Andalusian Center for Nanomedicine and Biotechnology-BIONAND, Málaga, Spain.
Universidad de Málaga, Málaga, Spain.

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