Replication of fMRI group activations in the neuroimaging battery for the Mainz Resilience Project (MARP).
Group activations
Intra class correlation
Jaccard index
Replication
fMRI
Journal
NeuroImage
ISSN: 1095-9572
Titre abrégé: Neuroimage
Pays: United States
ID NLM: 9215515
Informations de publication
Date de publication:
01 01 2020
01 01 2020
Historique:
received:
14
11
2018
revised:
16
09
2019
accepted:
23
09
2019
pubmed:
27
9
2019
medline:
28
11
2020
entrez:
27
9
2019
Statut:
ppublish
Résumé
Motivated by the recent replicability crisis we tested replicability of functional magnetic resonance imaging (fMRI) group activations in two independent samples. An identical behavioral and fMRI test battery for the longitudinal investigation of stress resilience mechanisms was developed for the Mainz Resilience Project (MARP) and conducted in a discovery (N = 54) and a replication sample (N = 103). The test battery consisted of a stress reactivity task, a reward sensitivity task, a fear conditioning and extinction paradigm, two volitional reappraisal tasks and an emotional interference inhibition task. Replicability of group activations was tested with the Jaccard index and the Intra Class Correlation (ICC). Overall, we observed good to excellent replicability of activations at the whole brain level. Only a minority of contrasts showed unsatisfactory replicability. Replicability at the level of individual regions of interest (ROIs) was generally lower. Tasks with stronger activation in the discovery sample showed better replicability.
Identifiants
pubmed: 31557545
pii: S1053-8119(19)30814-6
doi: 10.1016/j.neuroimage.2019.116223
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
116223Informations de copyright
Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.