Successful Treatment of Dermatophytomas in 19 Patients Using Efinaconazole 10% Solution.
Fungal infection
Nail disorder
Nail fungus
Onychomycosis
Journal
Skin appendage disorders
ISSN: 2296-9195
Titre abrégé: Skin Appendage Disord
Pays: Switzerland
ID NLM: 101670617
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
02
12
2017
accepted:
31
10
2018
entrez:
28
9
2019
pubmed:
29
9
2019
medline:
29
9
2019
Statut:
ppublish
Résumé
Dermatophytomas represent a historically difficult-to-treat complication of onychomycosis and are characterized by adherent fungal masses encased in biofilm in the subungual space. In this study, we evaluated the efficacy of 10% efinaconazole solution in patients with onychomycosis complicated by dermatophytomas. Cure was achieved in 65% of target great toenails. All dermatophytomas resolved and did not recur during the study. The median time to dermatophytoma resolution was 16 weeks.
Identifiants
pubmed: 31559255
doi: 10.1159/000495042
pii: sad-0005-0304
pmc: PMC6751476
doi:
Types de publication
Journal Article
Langues
eng
Pagination
304-308Déclaration de conflit d'intérêts
Boni Elewski, MD: Clinical research support – research funding to University: Abbvie; Boehringer Ingelheim; Celgene; Incyte; Lilly; Merck; Novartis; Pfizer; Regeneron; Sun; Viamet; Valeant. Consultant – received honorarium: Celgene; Lilly; Novartis; Pfizer; Sun; Valeant. The authors Casey Wang, Wendy Cantrell, and Theresa Canavan have no conflicts of interest to declare in this study.
Références
J Am Acad Dermatol. 2002 Oct;47(4):629-31
pubmed: 12271316
J Am Acad Dermatol. 2007 Jun;56(6):939-44
pubmed: 17307276
Arch Dermatol. 2011 Nov;147(11):1277-82
pubmed: 22106113
J Am Acad Dermatol. 2013 Apr;68(4):600-608
pubmed: 23177180
J Drugs Dermatol. 2015 May;14(5):524-6
pubmed: 25942674
J Am Acad Dermatol. 2015 Jul;73(1):62-9
pubmed: 25956661
J Drugs Dermatol. 2015 Aug;14(8):859-63
pubmed: 26267730
Clin Microbiol Rev. 1998 Jul;11(3):415-29
pubmed: 9665975