Utility of regional epithelial thickness measurements in corneal evaluations.

CXL LASIK LASIK complications OCT PRK Scheimpflug VHFDU corneal cross-linking ectasia epithelium thickness keratoconus ocular coherence tomography refractive surgery screening very high frequency digital ultrasound

Journal

Survey of ophthalmology
ISSN: 1879-3304
Titre abrégé: Surv Ophthalmol
Pays: United States
ID NLM: 0404551

Informations de publication

Date de publication:
Historique:
received: 13 02 2019
revised: 10 09 2019
accepted: 16 09 2019
pubmed: 29 9 2019
medline: 18 3 2021
entrez: 28 9 2019
Statut: ppublish

Résumé

The measurement of regional corneal epithelial thickness and characterization of its behavior in response to changes in corneal architecture are increasingly drawing interest in clinical practice. The epithelium has tremendous capacity for remodeling and does so in response to underlying stromal pathology or changes in anterior corneal curvature. Various remodeling patterns have been identified that help distinguish between ectatic and nonectatic corneal conditions. Epithelial mapping has also facilitated more precise, individualized corneal surface disorder treatments. We highlight the different imaging modalities for epithelium measurement, epithelial remodeling patterns in ectatic disorders and after corneal refractive surgery, discuss utility of epithelial measurement in therapeutic refractive surgery planning, and discuss controversies that exist regarding epithelial remodeling, including its mechanisms and its relative importance in surgical planning and screening evaluations.

Identifiants

pubmed: 31560871
pii: S0039-6257(19)30256-5
doi: 10.1016/j.survophthal.2019.09.003
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

187-204

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Eric S Hwang (ES)

Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Julie M Schallhorn (JM)

UCSF Department of Ophthalmology, San Francisco, CA, USA.

J Bradley Randleman (JB)

Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH, USA. Electronic address: randlej@ccf.org.

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Classifications MeSH