Moderate Intensity Resistive Training Reduces Oxidative Stress and Improves Muscle Mass and Function in Older Individuals.

muscle mass muscle strength oxidative stress resistive training

Journal

Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981

Informations de publication

Date de publication:
26 Sep 2019
Historique:
received: 09 09 2019
revised: 23 09 2019
accepted: 25 09 2019
entrez: 29 9 2019
pubmed: 29 9 2019
medline: 29 9 2019
Statut: epublish

Résumé

An innovative moderate-intensity resistive exercise-training (RT) program was tested in thirty-five sarcopenic elders (SAR). The subjects were randomized into two groups: SAR training (SAR-RT), n = 20, 73.0 ± 5.5 years, or SAR non-training (SAR-NT), n = 15, 71.7 ± 3.4 years. The training consisted of 12-week progressive RT, thrice/week, at 60% one-repetition maximum (1RM), 3 sets, 14-16 repetitions for both upper and lower limbs. The pre and post intervention measurements included: the skeletal muscle index (SMI%); strength (1RM); stair-climbing power (SCP); muscle thickness (MT) of vastus lateralis (VL) and elbow flexors (EF), VL pennation angle (PA), rectus femoris (RF) anatomical cross-sectional area (ACSA); reactive oxygen species (ROS), total antioxidant capacity (TAC), protein carbonyls (PC), thiobarbituric acid-reactive substances (TBARS), 8-isoprostane (8-iso-PGF2-α), 8-OH-2-deoxyguanosine (8-OH-dG), as markers of oxidative stress/damage (OxS). In SAR-RT, SCP increased by 7.7% (

Identifiants

pubmed: 31561586
pii: antiox8100431
doi: 10.3390/antiox8100431
pmc: PMC6826968
pii:
doi:

Types de publication

Journal Article

Langues

eng

Déclaration de conflit d'intérêts

The authors declare no conflicts of interest.

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Auteurs

Alessandra Vezzoli (A)

Institute of Clinical Physiology, National Research Council (CNR), ASST Grande Ospedale Metropolitano Niguarda, 20121 Milan, Italy. alessandra.vezzoli@cnr.it.

Simona Mrakic-Sposta (S)

Institute of Clinical Physiology, National Research Council (CNR), ASST Grande Ospedale Metropolitano Niguarda, 20121 Milan, Italy. simona.mrakicsposta@cnr.it.

Michela Montorsi (M)

Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, 20121 Milan, Italy. michela.montorsi@uniroma5.it.

Simone Porcelli (S)

Institute of Biomedical Technologies, National Research Council (CNR), Segrate, 20121 Milan, Italy. simone.porcelli@itb.cnr.it.

Paola Vago (P)

Interfaculty of Education and Medicine, Università Cattolica del Sacro Cuore, 20121 Milan, Italy. paola.vago@unicatt.it.

Ferdinando Cereda (F)

Interfaculty of Education and Medicine, Università Cattolica del Sacro Cuore, 20121 Milan, Italy. ferdinando.cereda@unicatt.it.

Stefano Longo (S)

Department of Biomedical Sciences for Health, Università degli Studi di Milano, 20133 Milan, Italy. stefano.longo@unimi.it.

Marcello Maggio (M)

Department of Clinical and Experimental Medicine, University of Parma, 43126 Parma, Italy. marcellogiuseppe.maggio@unipr.it.

Marco Narici (M)

Department of Biomedical Sciences, University of Padua, 35122 Padua, Italy. marco.narici@unipd.it.

Classifications MeSH