Could drug burden be associated with severe periodontitis in patients receiving haemodialysis?
Calcium channel blockers
Haemodialysis
Periodontitis
Polystyrene sulphonic acid
β antagonist
Journal
Journal of renal care
ISSN: 1755-6686
Titre abrégé: J Ren Care
Pays: United States
ID NLM: 101392167
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
pubmed:
30
9
2019
medline:
9
6
2020
entrez:
30
9
2019
Statut:
ppublish
Résumé
Periodontitis increases the risk of cardiovascular disease in the general population by triggering systemic inflammation. To investigate the relationship between systemic inflammation and periodontitis, and clarify any association between severe periodontitis and the medications used by patients receiving haemodialysis. A cross-sectional study. The study was undertaken with 56 patients receiving haemodialysis. Demographic and laboratory data and prescribed drugs regularly used by patients were recorded from hospital records. During the dialysis session, a validated Xerostomia Inventory score was completed. A complete dental/periodontal examination was also undertaken on all patients by the same periodontist. In the study population, stage I periodontitis was determined in 41%, stage II periodontitis in 17%, stage III periodontitis in 21%, and stage IV periodontitis in 21%. Male gender, hypertension, coronary artery disease, β antagonists, calcium channel blockers, sodium polystyrene sulphonate, teeth brushing less than twice a day and high sensitive C-reactive protein > 8 mg/l were significantly associated with severe periodontitis. Drugs, including β antagonists, calcium channel blockers, polystyrene sulphonate, co-morbid conditions and poor or insufficient oral care could facilitate an increase in the severity of periodontitis in patients receiving haemodialysis. Severe periodontitis also seems to be associated with cardiovascular disease and inflammation in patients with chronic renal disease.
Sections du résumé
BACKGROUND
BACKGROUND
Periodontitis increases the risk of cardiovascular disease in the general population by triggering systemic inflammation.
AIM
OBJECTIVE
To investigate the relationship between systemic inflammation and periodontitis, and clarify any association between severe periodontitis and the medications used by patients receiving haemodialysis.
DESIGN
METHODS
A cross-sectional study.
PARTICIPANTS
METHODS
The study was undertaken with 56 patients receiving haemodialysis.
MEASUREMENTS
METHODS
Demographic and laboratory data and prescribed drugs regularly used by patients were recorded from hospital records. During the dialysis session, a validated Xerostomia Inventory score was completed. A complete dental/periodontal examination was also undertaken on all patients by the same periodontist.
RESULTS
RESULTS
In the study population, stage I periodontitis was determined in 41%, stage II periodontitis in 17%, stage III periodontitis in 21%, and stage IV periodontitis in 21%. Male gender, hypertension, coronary artery disease, β antagonists, calcium channel blockers, sodium polystyrene sulphonate, teeth brushing less than twice a day and high sensitive C-reactive protein > 8 mg/l were significantly associated with severe periodontitis.
CONCLUSION
CONCLUSIONS
Drugs, including β antagonists, calcium channel blockers, polystyrene sulphonate, co-morbid conditions and poor or insufficient oral care could facilitate an increase in the severity of periodontitis in patients receiving haemodialysis. Severe periodontitis also seems to be associated with cardiovascular disease and inflammation in patients with chronic renal disease.
Substances chimiques
Prescription Drugs
0
Types de publication
Journal Article
Langues
eng
Pagination
239-247Informations de copyright
© 2019 European Dialysis and Transplant Nurses Association/European Renal Care Association.