Development of Bifunctional Three-Dimensional Cysts from Chemically Induced Liver Progenitors.


Journal

Stem cells international
ISSN: 1687-966X
Titre abrégé: Stem Cells Int
Pays: United States
ID NLM: 101535822

Informations de publication

Date de publication:
2019
Historique:
received: 07 06 2019
revised: 20 07 2019
accepted: 30 07 2019
entrez: 1 10 2019
pubmed: 1 10 2019
medline: 1 10 2019
Statut: epublish

Résumé

Chemically induced liver progenitors (CLiPs) have promising applications in liver regenerative medicine. Three-dimensional (3D) structures generated from liver progenitor cells possess wide applications in cell transplantation, disease model, and drug testing. Here, we report on the spontaneous formation of 3D cystic structures comprising maturing rat CLiPs on gelatin-coated dishes. Our 3D cysts contained Alb

Identifiants

pubmed: 31565060
doi: 10.1155/2019/3975689
pmc: PMC6745155
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3975689

Informations de copyright

Copyright © 2019 Yu Huang et al.

Déclaration de conflit d'intérêts

The authors declare that there is no conflict of interest regarding the publication of this paper.

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Auteurs

Yu Huang (Y)

Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
Department of Hepato-Pancreato-Biliary Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, China.

Yusuke Sakai (Y)

Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
Department of Chemical Engineering, Faculty of Engineering, Graduate School, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.

Takanobu Hara (T)

Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

Takeshi Katsuda (T)

Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

Takahiro Ochiya (T)

Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

Tomohiko Adachi (T)

Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

Masaaki Hidaka (M)

Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

Wei-Li Gu (WL)

Department of Hepato-Pancreato-Biliary Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, China.

Susumu Eguchi (S)

Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

Classifications MeSH