Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy.
CryoEM
SAXS
allostery
biochemistry
chemical biology
cyclic GMP
manduca sexta
nitric oxide
none
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
30 09 2019
30 09 2019
Historique:
received:
28
07
2019
accepted:
27
09
2019
pubmed:
1
10
2019
medline:
13
3
2020
entrez:
1
10
2019
Statut:
epublish
Résumé
Soluble guanylate cyclase (sGC) is the primary receptor for nitric oxide (NO) in mammalian nitric oxide signaling. We determined structures of full-length
Identifiants
pubmed: 31566566
doi: 10.7554/eLife.50634
pii: 50634
pmc: PMC6839917
doi:
pii:
Substances chimiques
Indazoles
0
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole
154453-18-6
Nitric Oxide
31C4KY9ESH
Soluble Guanylyl Cyclase
EC 4.6.1.2
Banques de données
PDB
['6PAS', '6PAT']
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIH HHS
ID : GM066698
Pays : United States
Organisme : NIH HHS
ID : GM127854
Pays : United States
Organisme : NIH HHS
ID : S10OD018483
Pays : United States
Organisme : NIGMS NIH HHS
ID : P30 GM124169
Pays : United States
Organisme : NIH HHS
ID : GM124169
Pays : United States
Commentaires et corrections
Type : CommentIn
Déclaration de conflit d'intérêts
BH, AY, DR, KM, MH, JH No competing interests declared, MM Reviewing editor, eLife
Références
Protein Sci. 2013 Oct;22(10):1439-44
pubmed: 23934793
Nat Chem Biol. 2017 Dec;13(12):1216-1221
pubmed: 28967923
Antioxid Redox Signal. 2017 Jan 20;26(3):107-121
pubmed: 26979942
Proteins. 2011 Mar;79(3):898-915
pubmed: 21287621
Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21602-7
pubmed: 20007374
Pharmacol Rev. 2000 Sep;52(3):375-414
pubmed: 10977868
Nature. 1997 Mar 20;386(6622):247-53
pubmed: 9069282
Nat Protoc. 2015 Jun;10(6):845-58
pubmed: 25950237
Blood. 1994 Dec 15;84(12):4226-33
pubmed: 7527671
J Comput Chem. 2004 Oct;25(13):1605-12
pubmed: 15264254
Nature. 2019 Oct;574(7777):206-210
pubmed: 31514202
BMC Struct Biol. 2010 Jan 27;10:2
pubmed: 20105301
J Struct Biol. 2015 Nov;192(2):216-21
pubmed: 26278980
Nat Methods. 2017 Mar;14(3):290-296
pubmed: 28165473
Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):12854-9
pubmed: 15326296
Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9821-E9828
pubmed: 29087332
J Biol Chem. 2008 Jul 25;283(30):20968-77
pubmed: 18515359
Structure. 2014 Apr 8;22(4):602-11
pubmed: 24560804
Angew Chem Int Ed Engl. 2013 Sep 2;52(36):9442-62
pubmed: 23963798
Acta Crystallogr D Biol Crystallogr. 2010 Jan;66(Pt 1):12-21
pubmed: 20057044
Biochemistry. 2008 Mar 25;47(12):3892-9
pubmed: 18302323
Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):E4156-64
pubmed: 25253889
BMC Struct Biol. 2008 Oct 07;8:42
pubmed: 18842118
Methods Mol Biol. 2014;1091:245-58
pubmed: 24203338
J Appl Crystallogr. 2013 Feb 1;46(Pt 1):1-13
pubmed: 23396808
Biochemistry. 2013 Mar 5;52(9):1568-82
pubmed: 23363317
Clin Genet. 2016 Oct;90(4):351-60
pubmed: 26777256
Proc Natl Acad Sci U S A. 1977 Aug;74(8):3203-7
pubmed: 20623
Free Radic Res. 1999 Dec;31(6):577-96
pubmed: 10630682
Biochemistry. 1994 May 10;33(18):5636-40
pubmed: 7910035
Q Rev Biophys. 2007 Aug;40(3):191-285
pubmed: 18078545
Biochem Biophys Res Commun. 2002 Apr 12;292(4):1057-62
pubmed: 11944922
Nat Rev Drug Discov. 2015 Sep;14(9):623-41
pubmed: 26265312
Gen Physiol Biophys. 2009 Jun;28(2):174-89
pubmed: 19592714
Prog Neurobiol. 2001 May;64(1):51-68
pubmed: 11250062
Biochemistry. 1998 Mar 31;37(13):4502-9
pubmed: 9521770
Biophys J. 2013 Aug 20;105(4):962-74
pubmed: 23972848
J Biol Chem. 1999 Mar 19;274(12):7599-602
pubmed: 10075642
Elife. 2018 Jun 01;7:
pubmed: 29856314
Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14753-8
pubmed: 10611285
Biochemistry. 2011 May 24;50(20):4291-7
pubmed: 21491881
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501
pubmed: 20383002
Science. 1997 Dec 12;278(5345):1907-16
pubmed: 9417641
J Biol Chem. 2018 Feb 2;293(5):1850-1864
pubmed: 29222330
PLoS One. 2013;8(3):e57644
pubmed: 23505436
Curr Opin Struct Biol. 1998 Dec;8(6):770-7
pubmed: 9914257
Am J Hum Genet. 2014 Mar 6;94(3):385-94
pubmed: 24581742
PLoS One. 2011;6(11):e26976
pubmed: 22096512
Neurology. 2011 Oct 18;77(16):1568-76
pubmed: 22006889
Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):2960-5
pubmed: 24516165
Nitric Oxide. 2018 Jul 1;77:65-74
pubmed: 29704567
Nucleic Acids Res. 2010 Jul;38(Web Server issue):W540-4
pubmed: 20507903
Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6777-82
pubmed: 23572573
Nature. 1987 Jun 11-17;327(6122):524-6
pubmed: 3495737
Nat Methods. 2009 Aug;6(8):606-12
pubmed: 19620974
Science. 2019 Apr 26;364(6438):389-394
pubmed: 31023924
Nature. 2013 Apr 25;496(7446):477-81
pubmed: 23619693
Biochemistry. 2005 Mar 15;44(10):4083-90
pubmed: 15751985
Pharmacol Rev. 1991 Jun;43(2):109-42
pubmed: 1852778
Biol Direct. 2006 Sep 05;1:25
pubmed: 16953892
Protein Sci. 2000 Sep;9(9):1753-73
pubmed: 11045621
Biochemistry. 2014 Apr 8;53(13):2153-65
pubmed: 24669844
Nat Methods. 2017 Apr;14(4):331-332
pubmed: 28250466
J Synchrotron Radiat. 2010 Nov;17(6):774-81
pubmed: 20975223
Circulation. 2011 May 24;123(20):2263-73
pubmed: 21606405
Nitric Oxide. 2009 Nov-Dec;21(3-4):149-56
pubmed: 19635579
Annu Rev Biochem. 2012;81:533-59
pubmed: 22404633
Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13064-9
pubmed: 16131543
EMBO J. 2004 Nov 10;23(22):4443-50
pubmed: 15510222
Nucleic Acids Res. 2016 Jul 8;44(W1):W424-9
pubmed: 27151198
J Struct Biol. 2012 Dec;180(3):519-30
pubmed: 23000701