Acceptance of pregnant women's vaccination against pertussis among French women and health professionals: PREVACOQ-1 and -2 studies.


Journal

Medecine et maladies infectieuses
ISSN: 1769-6690
Titre abrégé: Med Mal Infect
Pays: France
ID NLM: 0311416

Informations de publication

Date de publication:
Nov 2019
Historique:
received: 28 07 2018
revised: 16 10 2018
accepted: 02 09 2019
pubmed: 2 10 2019
medline: 22 5 2020
entrez: 2 10 2019
Statut: ppublish

Résumé

Protection of French young infants against pertussis only relies on their relatives' vaccination. The alternative is vaccination of pregnant women against pertussis (cocooning strategy), but this strategy is not yet recommended in France. We assessed the acceptance of this strategy among French postpartum women and health professionals. We performed a multicenter survey in 2016 among postpartum women and health professionals (family physicians, obstetricians-gynecologists, midwives, and medical students) to determine the acceptance of anti-pertussis vaccination. We evaluated knowledge, perception, and attitude towards vaccination to identify factors associated with acceptance. Questionnaires were completed by 52% (1208/2337) of women and 40% (694/1754) of health professionals. Seventy-seven per cent of women (95% CI: 74-79) and 93% of health professionals (95% CI: 91-95) were favorable to anti-pertussis vaccination of pregnant women. Thirty-three per cent (227/687) of health professionals believed that pertussis induced life-long immunity and 20% (136/687) of them were not aware of the cocooning strategy. In multivariate analysis, factors associated with acceptance among women were younger age, higher knowledge, having received advice during pregnancy, being vaccinated against influenza, and having never refused any vaccine; among health professionals, factors associated with acceptance were belief that inactivated vaccines are obstetrically safe, regular practice of influenza vaccination in pregnant women, pertussis cocooning strategy, and never prescribing preventive homeopathy for influenza. Vaccination of pregnant women against pertussis should be well-accepted by informed mothers and health professionals. If this strategy were to be implemented in France, efforts should be made towards adequate information.

Identifiants

pubmed: 31570170
pii: S0399-077X(18)30780-7
doi: 10.1016/j.medmal.2019.09.001
pii:
doi:

Substances chimiques

Pertussis Vaccine 0

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

593-601

Informations de copyright

Copyright © 2019. Published by Elsevier Masson SAS.

Auteurs

M Lefebvre (M)

Inserm, CIC 1413, centre de prévention des maladies infectieuses et transmissibles, centre hospitalo-universitaire de Nantes, 5, rue du Professeur-Yves-Boquien, 44000 Nantes, France; Inserm, CIC 1413, service de maladies infectieuses et tropicales, centre hospitalo-universitaire de Nantes, 1, place Alexis-Ricordeau, 44000 Nantes, France. Electronic address: maeva.lefebvre@chu-nantes.fr.

O Grossi (O)

Service de médecine interne et maladies infectieuses, l'hôpital privé du confluent, 2-4, rue Eric-Tabarly, 44200 Nantes, France.

M Chalopin (M)

Inserm, CIC 1413, centre de prévention des maladies infectieuses et transmissibles, centre hospitalo-universitaire de Nantes, 5, rue du Professeur-Yves-Boquien, 44000 Nantes, France.

C Ferré (C)

Inserm, CIC 1413, centre de prévention des maladies infectieuses et transmissibles, centre hospitalo-universitaire de Nantes, 5, rue du Professeur-Yves-Boquien, 44000 Nantes, France.

E Prel (E)

Service de gynécologie obstétrique centre hospitalo-universitaire de Nantes, 35, boulevard Jean-Monnet, 44000 Nantes, France.

J Coutherut (J)

Inserm, CIC 1413, centre de prévention des maladies infectieuses et transmissibles, centre hospitalo-universitaire de Nantes, 5, rue du Professeur-Yves-Boquien, 44000 Nantes, France.

V Briend-Godet (V)

Inserm, CIC 1413, centre de prévention des maladies infectieuses et transmissibles, centre hospitalo-universitaire de Nantes, 5, rue du Professeur-Yves-Boquien, 44000 Nantes, France.

C Biron (C)

Inserm, CIC 1413, centre de prévention des maladies infectieuses et transmissibles, centre hospitalo-universitaire de Nantes, 5, rue du Professeur-Yves-Boquien, 44000 Nantes, France; Inserm, CIC 1413, service de maladies infectieuses et tropicales, centre hospitalo-universitaire de Nantes, 1, place Alexis-Ricordeau, 44000 Nantes, France.

F Raffi (F)

Inserm, CIC 1413, service de maladies infectieuses et tropicales, centre hospitalo-universitaire de Nantes, 1, place Alexis-Ricordeau, 44000 Nantes, France.

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Classifications MeSH