Comparison of the Utilities of Cryobiopsy and Forceps Biopsy for Peripheral Lung Cancer.


Journal

Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988

Informations de publication

Date de publication:
Oct 2019
Historique:
received: 23 07 2019
revised: 05 08 2019
accepted: 07 08 2019
entrez: 2 10 2019
pubmed: 2 10 2019
medline: 8 10 2019
Statut: ppublish

Résumé

This study aimed to compare the efficacies of cryobiopsy and forceps biopsy for peripheral lung cancer detection. A retrospective review of peripheral lung cancer cases between December 2017 and April 2019 was conducted. Forceps biopsy was performed followed by cryobiopsy using a guide sheath (GS). Diagnostic yields were compared between cryobiopsy and forceps biopsy. A total of 53 lung cancer lesions were evaluated. The diagnostic yields of forceps biopsy and cryobiopsy were 86.8% and 81.1%, respectively. Univariate and multivariate analyses indicated that cryobiopsy with a GS was significantly associated with increased diagnostic yield (odds ratio(OR)=11.6; p=0.044). Among the four patients who tested positive on cryobiopsy and negative on forceps biopsy, one had diffused pulmonary metastases and the others showed intratumoural air bronchograms. Cryobiopsy using a GS can significantly increase diagnostic yield and help identify lesions with intratumoural air bronchograms and external wall lesions.

Sections du résumé

BACKGROUND/AIM OBJECTIVE
This study aimed to compare the efficacies of cryobiopsy and forceps biopsy for peripheral lung cancer detection.
PATIENTS AND METHODS METHODS
A retrospective review of peripheral lung cancer cases between December 2017 and April 2019 was conducted. Forceps biopsy was performed followed by cryobiopsy using a guide sheath (GS). Diagnostic yields were compared between cryobiopsy and forceps biopsy.
RESULTS RESULTS
A total of 53 lung cancer lesions were evaluated. The diagnostic yields of forceps biopsy and cryobiopsy were 86.8% and 81.1%, respectively. Univariate and multivariate analyses indicated that cryobiopsy with a GS was significantly associated with increased diagnostic yield (odds ratio(OR)=11.6; p=0.044). Among the four patients who tested positive on cryobiopsy and negative on forceps biopsy, one had diffused pulmonary metastases and the others showed intratumoural air bronchograms.
CONCLUSION CONCLUSIONS
Cryobiopsy using a GS can significantly increase diagnostic yield and help identify lesions with intratumoural air bronchograms and external wall lesions.

Identifiants

pubmed: 31570467
pii: 39/10/5683
doi: 10.21873/anticanres.13766
doi:

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

5683-5688

Informations de copyright

Copyright© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Auteurs

Shingo Nasu (S)

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan hugurahoma@yahoo.co.jp.

Norio Okamoto (N)

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

Hidekazu Suzuki (H)

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

Takayuki Shiroyama (T)

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

Ayako Tanaka (A)

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

Yumiko Samejima (Y)

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

Tomohiro Kanai (T)

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

Yoshimi Noda (Y)

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

Satomu Morita (S)

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

Naoko Morishita (N)

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

Kayo Ueda (K)

Department of Pathology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

Kunimitsu Kawahara (K)

Department of Pathology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

Tomonori Hirashima (T)

Department of Thoracic Oncology, Osaka Prefectural Hospital Organization, Osaka Habikino Medical Center, Osaka, Japan.

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Classifications MeSH