Age Is Not a Criterion in Patient Selection for Kasai Portoenterostomy.
Age
Kasai portoenterostomy
biliary atresia
Journal
Journal of Indian Association of Pediatric Surgeons
ISSN: 0971-9261
Titre abrégé: J Indian Assoc Pediatr Surg
Pays: India
ID NLM: 101179870
Informations de publication
Date de publication:
Historique:
entrez:
2
10
2019
pubmed:
2
10
2019
medline:
2
10
2019
Statut:
ppublish
Résumé
The aim of our study was to compare the outcome of Kasai portoenterostomy (KPE) in children with biliary atresia (BA) older than 90 days to children less than 90 days and to study its safety and efficacy in children older than 90 days. Relevant data were collected from our prospectively maintained database of all children with BA who underwent KPE over a 5-year period. Children were divided into two groups: Group 1 ≤90 days and Group 2 >90 days. Data analyzed and compared included total and direct bilirubin, aspartate aminotransferase-to-platelet ratio index (APRI), and the outcome of procedure which was defined as a serum direct bilirubin <2 mg/dl within 6 months after surgery. Standard statistical tests were used for analysis. Out of 62 children, 45 children were in Group 1 and 17 children were in Group 2. Children in Group 2 had similar total and direct bilirubin compared to children in Group 1. APRI, an indicator of fibrosis, was significantly increased in Group 2 ( KPE was successful in a third of children over 90 days of age and can be safely performed in this group. In the absence of synthetic liver failure, age should not be a disqualification for performing KPE.
Identifiants
pubmed: 31571758
doi: 10.4103/jiaps.JIAPS_182_18
pii: JIAPS-24-271
pmc: PMC6752066
doi:
Types de publication
Journal Article
Langues
eng
Pagination
271-274Informations de copyright
Copyright: © 2019 Journal of Indian Association of Pediatric Surgeons.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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