Biomarkers In Chronic Spontaneous Urticaria: Current Targets And Clinical Implications.
angiogenesis
biomarkers
chronic urticaria
inflammation
Journal
Journal of asthma and allergy
ISSN: 1178-6965
Titre abrégé: J Asthma Allergy
Pays: New Zealand
ID NLM: 101543450
Informations de publication
Date de publication:
2019
2019
Historique:
received:
12
07
2019
accepted:
05
09
2019
entrez:
2
10
2019
pubmed:
2
10
2019
medline:
2
10
2019
Statut:
epublish
Résumé
Chronic urticaria (CU) is a mast cell-driven disease characterized by the development of wheals, angioedema, or both for more than 6 weeks. The two major sub-types are chronic spontaneous urticaria (CSU) and inducible urticaria. In the last decade different pathophysiological mechanisms, potentially responsible for the development of the disease, have been described. It is likely that the activation of mast cells and basophils in CSU can be the results of immune system dysregulation, activation of the inflammatory cascade, and of the extrinsic coagulation pathway. Some of the mediators involved in the pathophysiological mechanisms of CSU have recently been identified as potential biomarkers useful for the diagnosis, follow-up, and management of the disease, even if they are not yet available in clinical practice. Thus, in this review we discuss new insights in the mediators involved in the pathogenesis of CSU, highlighting their potential role as biomarkers in the activity and progression of the disease and response to therapies.
Identifiants
pubmed: 31571935
doi: 10.2147/JAA.S184986
pii: 184986
pmc: PMC6759208
doi:
Types de publication
Journal Article
Langues
eng
Pagination
285-295Informations de copyright
© 2019 Puxeddu et al.
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest in this work.
Références
J Clin Invest. 1995 Dec;96(6):2606-12
pubmed: 8675625
Br J Dermatol. 2000 Aug;143(2):365-72
pubmed: 10951147
J Allergy Clin Immunol. 2013 Oct;132(4):983-6
pubmed: 23763979
Clin Exp Allergy. 2002 Feb;32(2):217-23
pubmed: 11929485
Int J Dermatol. 2010 May;49(5):579-84
pubmed: 20534097
J Cutan Med Surg. 2009 Jul-Aug;13(4):198-203
pubmed: 19706227
J Eur Acad Dermatol Venereol. 2019 May;33(5):918-924
pubmed: 30451325
Allergol Int. 2019 Apr;68(2):270-273
pubmed: 30355455
J Allergy Clin Immunol Pract. 2018 Jul - Aug;6(4):1386-1388.e1
pubmed: 29175369
Allergy. 2008 Feb;63(2):176-80
pubmed: 17961199
Acta Derm Venereol. 2017 Jun 9;97(6):698-704
pubmed: 28303277
Am J Med Sci. 2010 Jun;339(6):504-8
pubmed: 20400886
J Korean Med Sci. 2014 Jan;29(1):43-7
pubmed: 24431904
J Allergy Clin Immunol. 1999 Jul;104(1):169-72
pubmed: 10400855
Acta Derm Venereol. 2004;84(4):288-90
pubmed: 15339073
J Allergy Clin Immunol Pract. 2016 May-Jun;4(3):529-30
pubmed: 26725153
J Eur Acad Dermatol Venereol. 2016 Mar;30(3):454-5
pubmed: 25371135
Allergy Asthma Immunol Res. 2016 Mar;8(2):115-23
pubmed: 26739404
Postepy Dermatol Alergol. 2017 Oct;34(5):448-452
pubmed: 29507559
J Biol Chem. 2006 Sep 8;281(36):26069-80
pubmed: 16835222
Mediators Inflamm. 2019 Apr 17;2019:9213074
pubmed: 31148950
Clin Transl Allergy. 2012 Oct 01;2(1):19
pubmed: 23025508
Cytokine. 2013 Mar;61(3):741-3
pubmed: 23433789
Proc Natl Acad Sci U S A. 1991 May 15;88(10):4220-4
pubmed: 1709737
J Allergy Clin Immunol. 2017 Mar;139(3):1059-1061.e1
pubmed: 27838346
Biomed Res Int. 2018 Nov 1;2018:9856843
pubmed: 30515422
J Clin Lab Anal. 2004;18(1):9-13
pubmed: 14730551
J Immunol Res. 2018 Nov 21;2018:5615109
pubmed: 30584542
Mol Immunol. 2009 Sep;46(14):2753-66
pubmed: 19477527
Clin Exp Allergy. 2003 Mar;33(3):337-41
pubmed: 12614448
Allergy. 2009 Sep;64(9):1256-68
pubmed: 19650847
Clin Exp Dermatol. 2007 Sep;32(5):568-70
pubmed: 17509061
Asian Pac J Allergy Immunol. 2016 Sep;34(3):201-205
pubmed: 27001657
Rev Alerg Mex. 2015 Oct-Dec;62(4):279-86
pubmed: 26556663
Clin Lab. 2015;61(9):1283-8
pubmed: 26554248
Int Arch Allergy Immunol. 2003 Oct;132(2):177-82
pubmed: 14600430
J Allergy Clin Immunol. 2015 May;135(5):1401-3
pubmed: 25542882
Clin Immunol. 2005 Mar;114(3):284-92
pubmed: 15721839
J Invest Dermatol. 1994 May;102(5):803-6
pubmed: 7513741
Ann Dermatol. 2015 Aug;27(4):423-30
pubmed: 26273159
Int Arch Allergy Immunol. 2017;172(1):40-44
pubmed: 28219067
Indian J Dermatol. 2015 May-Jun;60(3):323
pubmed: 26120186
PLoS One. 2011 Apr 12;6(4):e14794
pubmed: 21532759
Clin Exp Allergy. 2009 Jun;39(6):777-87
pubmed: 19400905
Clin Exp Allergy. 1997 Dec;27(12):1417-24
pubmed: 9433937
Clin Transl Allergy. 2017 Jan 10;7:1
pubmed: 28078079
J Allergy Clin Immunol. 2012 May;129(5):1307-13
pubmed: 22336078
Clin Exp Allergy. 2016 Feb;46(2):275-87
pubmed: 26545308
J Eur Acad Dermatol Venereol. 2017 Jun;31(6):964-971
pubmed: 28299827
Clin Exp Dermatol. 2014 Oct;39(7):795-800
pubmed: 25196271
Dermatology. 2006;212(2):150-9
pubmed: 16484822
Acta Derm Venereol. 2013 Mar 27;93(2):156-60
pubmed: 22948845
Clin Exp Allergy. 2005 Feb;35(2):221-5
pubmed: 15725195
N Engl J Med. 2007 Jul 19;357(3):266-81
pubmed: 17634462
J Korean Med Sci. 2015 Jun;30(6):705-9
pubmed: 26028921
J Am Coll Surg. 2017 Dec;225(6):806-816
pubmed: 28923691
Allergy. 2009 Jun;64(6):927-36
pubmed: 19453340
Expert Rev Clin Immunol. 2016;12(3):229-31
pubmed: 26630120
Allergy. 2018 Jul;73(7):1393-1414
pubmed: 29336054
J Allergy Clin Immunol. 2017 Jun;139(6):1772-1781.e1
pubmed: 27777182
Int J Immunopathol Pharmacol. 2018 Jan-Dec;31:394632017750440
pubmed: 29268639
Arch Dermatol Res. 2011 Nov;303(9):643-9
pubmed: 21448661
J Allergy Clin Immunol. 2005 Sep;116(3):531-6
pubmed: 16159620
J Investig Dermatol Symp Proc. 2001 Nov;6(2):139-40
pubmed: 11764301
Allergy. 2006 Dec;61(12):1489-90
pubmed: 17073886
Asia Pac Allergy. 2013 Apr;3(2):100-5
pubmed: 23667833
Nat Med. 1995 Jan;1(1):27-31
pubmed: 7584949
Clin Exp Allergy. 2011 Oct;41(10):1386-91
pubmed: 21645137
Science. 1989 Dec 8;246(4935):1306-9
pubmed: 2479986
Allergy. 2011 Mar;66(3):428-33
pubmed: 21083568
Arch Dermatol Res. 2014 Mar;306(2):197-200
pubmed: 23995607
J Allergy Clin Immunol. 2018 Sep;142(3):876-882
pubmed: 29208545
Acta Derm Venereol. 2019 May 1;99(6):571-578
pubmed: 30809682
J Eur Acad Dermatol Venereol. 2014 Apr;28(4):469-74
pubmed: 23451767
Allergy. 2009 Nov;64(11):1616-22
pubmed: 19485983
Biomed Res Int. 2014;2014:650913
pubmed: 25025065
J Eur Acad Dermatol Venereol. 2016 Sep;30(9):1527-30
pubmed: 27004766
Clin Chim Acta. 2011 Jun 11;412(13-14):1171-9
pubmed: 21419112
Int Arch Allergy Immunol. 2016;171(2):102-110
pubmed: 27902979
PLoS One. 2015 Jun 09;10(6):e0129456
pubmed: 26057532
Clin Exp Allergy. 2017 Jan;47(1):19-36
pubmed: 27926978
Allergy Rhinol (Providence). 2017 Jun 1;8(2):67-80
pubmed: 28583230
Int Arch Allergy Immunol. 2010;153(3):288-93
pubmed: 20484928
J Invest Dermatol. 2002 Apr;118(4):658-63
pubmed: 11918713
Eur Ann Allergy Clin Immunol. 2017 Jul;49(4):189-192
pubmed: 28752724
Br J Dermatol. 2008 Sep;159(3):743-4
pubmed: 18616787
Nature. 1997 Apr 17;386(6626):671-4
pubmed: 9109485
Allergy. 2013 Feb;68(2):229-35
pubmed: 23205732
Circ Res. 2006 May 12;98(9):1203-11
pubmed: 16574906
Front Immunol. 2019 Mar 29;10:627
pubmed: 30984191
Allergy Asthma Immunol Res. 2019 Jan;11(1):29-42
pubmed: 30479075
J Immunol. 2000 May 1;164(9):4443-51
pubmed: 10779743
Ann Dermatol. 2014 Apr;26(2):145-9
pubmed: 24882966
Theranostics. 2017 Mar 6;7(5):1266-1276
pubmed: 28435464
Allergy. 2018 Dec;73(12):2406-2408
pubmed: 30076605
Allergy. 2018 Apr;73(4):940-948
pubmed: 29130488
PLoS One. 2015 Dec 23;10(12):e0145751
pubmed: 26699882
J Allergy Clin Immunol Pract. 2018 Jul - Aug;6(4):1108-1117
pubmed: 30033912
J Clin Immunol. 2006 Jul;26(4):299-307
pubmed: 16652230
Allergy. 2004 Aug;59(8):869-73
pubmed: 15230821
Clin Exp Allergy. 2010 Jun;40(6):875-81
pubmed: 20214668
Mediators Inflamm. 2015;2015:246126
pubmed: 25944979
J Allergy Clin Immunol. 1999 Jun;103(6):1216-7
pubmed: 10359911
Allergy Asthma Immunol Res. 2016 Nov;8(6):522-6
pubmed: 27582403
Allergy. 2014 Jun;69(6):683-91
pubmed: 24673528
Exp Dermatol. 2010 May;19(5):464-6
pubmed: 20163453
Int Arch Allergy Immunol. 2013;162(4):330-4
pubmed: 24157824
Br J Dermatol. 2014 Sep;171(3):505-11
pubmed: 24665899
J Inflamm (Lond). 2013 May 24;10(1):22
pubmed: 23706062
Int J Biochem Cell Biol. 2003 Dec;35(12):1601-7
pubmed: 12962699
J Allergy Clin Immunol. 2002 Jan;109(1):114-8
pubmed: 11799375