E-selectin gene haplotypes are associated with the risk of myocardial infarction.

E-selectin gene coronary artery disease haplotypes myocardial infarction tagging single nucleotide polymorphisms

Journal

Archives of medical science : AMS
ISSN: 1734-1922
Titre abrégé: Arch Med Sci
Pays: Poland
ID NLM: 101258257

Informations de publication

Date de publication:
Sep 2019
Historique:
received: 30 08 2018
accepted: 28 11 2018
entrez: 2 10 2019
pubmed: 2 10 2019
medline: 2 10 2019
Statut: ppublish

Résumé

Endothelial dysfunction is one of the most important factors implicated in the pathogenesis of coronary artery disease (CAD). The aim of this study was to investigate the association of the E-selectin gene ( A total of 379 Polish patients who had undergone angiography were included: 261 patients with angiographically documented CAD, 202 CAD patients without myocardial infarction (CAD/MI(-) group) and 59 patients with myocardial infarction (CAD/MI(+) group) as well as 118 healthy control subjects (non-CAD). Eight tagging single nucleotide polymorphisms (SNPs) in the The most common Our results suggest that

Identifiants

pubmed: 31572467
doi: 10.5114/aoms.2019.84413
pii: 36371
pmc: PMC6764297
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1223-1231

Informations de copyright

Copyright: © 2019 Termedia & Banach.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Jarosław Gorący (J)

Clinic of Cardiology, Pomeranian Medical University, Szczecin, Poland.

Mariusz Kaczmarczyk (M)

Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin, Poland.

Andrzej Ciechanowicz (A)

Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin, Poland.

Krzysztof Safranow (K)

Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland.

Joanna Gorący (J)

Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin, Poland.

Katarzyna Jakubowska (K)

Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland.

Dariusz Chlubek (D)

Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland.

Iwona Gorący (I)

Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin, Poland.

Classifications MeSH