Direct evaluation of peripheral airways using ultra-high-resolution CT in chronic obstructive pulmonary disease.
Chronic obstructive pulmonary disease
Computed tomography
Emphysema
Lung
Small airway
Journal
European journal of radiology
ISSN: 1872-7727
Titre abrégé: Eur J Radiol
Pays: Ireland
ID NLM: 8106411
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
12
07
2019
revised:
04
09
2019
accepted:
17
09
2019
pubmed:
2
10
2019
medline:
7
2
2020
entrez:
2
10
2019
Statut:
ppublish
Résumé
Disease in small airways <2 mm in diameter is a major pathology of chronic obstructive pulmonary disease (COPD). However, compared to airways <1 mm in diameter, the pathophysiological role of airways 1-2 mm in diameter remains unclear. This study analysed phantom and human COPD data to test the hypothesis that ultra-high-resolution computed tomography (U-HRCT) can accurately measure peripheral airways that are difficult to measure with conventional CT. The lower limit of lumen sizes measurable on U-HRCT was determined using phantom tubes. In the cross-sectional data of 110 males with COPD who underwent U-HRCT (1024 × 1024 matrix, 0.25 mm slice thickness) and spirometry, all 3 The errors in measuring the lumen area (LA) of phantom tubes ≥1.3 and 1.0 mm in diameter were within ±10 and -24%, respectively. The internal diameters for 70 and 62% of the 6 U-HRCT enables accurate and direct evaluation of peripheral airways 1-2 mm in diameter. The 6
Identifiants
pubmed: 31574362
pii: S0720-048X(19)30337-7
doi: 10.1016/j.ejrad.2019.108687
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
108687Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.