Endobronchial ultrasound-guided transbronchial needle aspiration versus mediastinoscopy for mediastinal staging of lung cancer: A protocol for a systematic review of economic evaluation studies.
Journal
Medicine
ISSN: 1536-5964
Titre abrégé: Medicine (Baltimore)
Pays: United States
ID NLM: 2985248R
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
entrez:
3
10
2019
pubmed:
3
10
2019
medline:
15
10
2019
Statut:
ppublish
Résumé
Lung cancer is a major health problem, with estimates of 1.6 million tumor-related deaths annually worldwide. The emergence of endobronchial ultrasound (EBUS), a minimally invasive procedure capable of providing valuable information for primary tumor diagnosis and mediastinal staging, significantly changed the approach of pulmonary cancer, becoming part of the routine mediastinal evaluation of lung cancer in developed countries. Some economic evaluation studies published in the last 10 years have already analyzed the incorporation of the EBUS technique in different health systems. The aim of this systematic review is to synthesize the relevant information brought by these studies to better understand the economic effect of the implementation of this staging tool. The systematic review will be reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement guidelines. Eletronic databases (Medline, Lilacs, Embase, Cochrane Library of Trials, Web of Science, Scopus, National Health System Economic Evaluation Database) will be searched for full economic analyses regarding the use of EBUS-guided transbronchial needle aspiration (EBUS-TBNA) compared to the surgical technique of mediastinoscopy for the mediastinal staging of lung cancer. Two authors will perform the selection of studies, data extraction, and the assessment of risk of bias. Occasionally, a senior reviewer will participate, if necessary, on study selection or data extraction. Results will be published in a peer-reviewed journal. This review may influence a more cost-effective mediastinal staging approach for patients with lung cancer around the world and help health decision makers decide whether the EBUS-TBNA technique should be incorporated into their health systems and how to do it efficiently. PROSPERO 42019107901.
Sections du résumé
BACKGROUND
BACKGROUND
Lung cancer is a major health problem, with estimates of 1.6 million tumor-related deaths annually worldwide. The emergence of endobronchial ultrasound (EBUS), a minimally invasive procedure capable of providing valuable information for primary tumor diagnosis and mediastinal staging, significantly changed the approach of pulmonary cancer, becoming part of the routine mediastinal evaluation of lung cancer in developed countries. Some economic evaluation studies published in the last 10 years have already analyzed the incorporation of the EBUS technique in different health systems. The aim of this systematic review is to synthesize the relevant information brought by these studies to better understand the economic effect of the implementation of this staging tool.
METHODS
METHODS
The systematic review will be reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement guidelines. Eletronic databases (Medline, Lilacs, Embase, Cochrane Library of Trials, Web of Science, Scopus, National Health System Economic Evaluation Database) will be searched for full economic analyses regarding the use of EBUS-guided transbronchial needle aspiration (EBUS-TBNA) compared to the surgical technique of mediastinoscopy for the mediastinal staging of lung cancer. Two authors will perform the selection of studies, data extraction, and the assessment of risk of bias. Occasionally, a senior reviewer will participate, if necessary, on study selection or data extraction.
RESULTS
RESULTS
Results will be published in a peer-reviewed journal.
CONCLUSION
CONCLUSIONS
This review may influence a more cost-effective mediastinal staging approach for patients with lung cancer around the world and help health decision makers decide whether the EBUS-TBNA technique should be incorporated into their health systems and how to do it efficiently.
PROTOCOL REGISTRY
UNASSIGNED
PROSPERO 42019107901.
Identifiants
pubmed: 31574837
doi: 10.1097/MD.0000000000017242
pii: 00005792-201909270-00046
pmc: PMC6775412
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e17242Références
Health Technol Assess. 2012;16(18):1-75, iii-iv
pubmed: 22472180
J Thorac Cardiovasc Surg. 2017 Jun;153(6):1567-1578
pubmed: 28283236
Chest. 2013 May;143(5 Suppl):e211S-e250S
pubmed: 23649440
Ann Thorac Surg. 2016 Nov;102(5):1747-1755
pubmed: 27637288
BMJ. 2013 Mar 25;346:f1049
pubmed: 23529982
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Value Health. 2013 Jan-Feb;16(1):57-65
pubmed: 23337216
Respiration. 2014;87(1):3-8
pubmed: 24296947
PLoS Med. 2009 Jul 21;6(7):e1000097
pubmed: 19621072
Am J Respir Crit Care Med. 2014 Mar 15;189(6):640-9
pubmed: 24484269