Molecular Inhibitor of QSOX1 Suppresses Tumor Growth
Journal
Molecular cancer therapeutics
ISSN: 1538-8514
Titre abrégé: Mol Cancer Ther
Pays: United States
ID NLM: 101132535
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
received:
12
03
2019
revised:
01
07
2019
accepted:
24
09
2019
pubmed:
3
10
2019
medline:
15
12
2020
entrez:
3
10
2019
Statut:
ppublish
Résumé
Quiescin sulfhydryl oxidase 1 (QSOX1) is an enzyme overexpressed by many different tumor types. QSOX1 catalyzes the formation of disulfide bonds in proteins. Because short hairpin knockdowns (KD) of QSOX1 have been shown to suppress tumor growth and invasion
Identifiants
pubmed: 31575656
pii: 1535-7163.MCT-19-0233
doi: 10.1158/1535-7163.MCT-19-0233
pmc: PMC6946859
mid: NIHMS1540742
doi:
Substances chimiques
Oxidoreductases Acting on Sulfur Group Donors
EC 1.8.-
QSOX1 protein, human
EC 1.8.3.2
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
112-122Subventions
Organisme : NCI NIH HHS
ID : P30 CA030199
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA078383
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA201226
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA224917
Pays : United States
Informations de copyright
©2019 American Association for Cancer Research.
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