Leptomeningeal Carcinomatosis from Squamous Cell Carcinoma of the Ethmoid Sinus: A Case Report.
cerebrospinal fluid
head
leptomeningeal carcinomatosis
metastasis
sinonasal cancer
sinus
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
30 Jul 2019
30 Jul 2019
Historique:
entrez:
3
10
2019
pubmed:
3
10
2019
medline:
3
10
2019
Statut:
epublish
Résumé
Leptomeningeal carcinomatosis (LMC) is an end-stage disease with poor prognosis. This disease has not yet been reported with sinonasal carcinomatosis. We present a case of a patient who presented with posterior ethmoid/anterior cranial mass which turned out to be poorly differentiated squamous cell carcinoma (SCC). Later the patient presented with enhancement of the spinal roots and a lumbar puncture diagnosed the leptomeningeal spread of her primary disease. After intrathecal chemotherapy and palliative radiation, the patient failed to resist her disease seven months after the diagnosis. We present the first case report of leptomeningeal spread of sinonasal cancer. Although it seems rare, LMC should be on the differential of patients presenting with neurological deficits.
Identifiants
pubmed: 31576272
doi: 10.7759/cureus.5281
pmc: PMC6764644
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e5281Informations de copyright
Copyright © 2019, Zammar et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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