Trends in thyroid carcinoma among thyroidectomy patients: a 12-year multicenter study.
Journal
Annals of Saudi medicine
ISSN: 0975-4466
Titre abrégé: Ann Saudi Med
Pays: Saudi Arabia
ID NLM: 8507355
Informations de publication
Date de publication:
Historique:
entrez:
4
10
2019
pubmed:
4
10
2019
medline:
23
2
2020
Statut:
ppublish
Résumé
Thyroid malignancy, the most diagnosed cancer of the endocrine system, represents 2% of all malignancies worldwide. The increasing incidence of thyroid cancer has been linked to the increasing sensitivity of modern diagnostic methods which overdiagnosis small thyroid tumors. Assess the distribution and trends in thyroid cancer among thyroidectomy patients. Descriptive, based on medical record review. Two tertiary care centers in Riyadh. We included patients who underwent thyroid surgery from January 1, 2004 to December 31, 2016 who ranged in age from 9-90 years regardless of initial diagnosis. Distribution of thyroid carcinomas by type, age and sex and trends over the time period. 979 patients. Of 979 patients, 84.5% were <55 years old, with the majority being female. Thyroid malignancy ranked second to benign tumors, and the most common type of thyroid cancer was papillary thyroid carcinoma (91% of malignant tumors), followed by follicular thyroid cancer (4.7% of malignant tumors). After thyroid microcarcinomas were isolated from the sample and studied separately, we found the overall trend for thyroid cancer to be stable, and that the annual increases in rates were due to increased diagnosis of thyroid microcarcinoma in the period from 2010 to 2016. Our study shows that increases in thyroid cancers may be attributed to a rise in the rates of diagnosis of thyroid microcarcinomas. The main limitation is the retrospective nature of this design. Also, a multicenter collaboration would prove beneficial in evaluating the trends of thyroid cancer in Saudi Arabia on a much larger scale. None.
Sections du résumé
BACKGROUND
BACKGROUND
Thyroid malignancy, the most diagnosed cancer of the endocrine system, represents 2% of all malignancies worldwide. The increasing incidence of thyroid cancer has been linked to the increasing sensitivity of modern diagnostic methods which overdiagnosis small thyroid tumors.
OBJECTIVES
OBJECTIVE
Assess the distribution and trends in thyroid cancer among thyroidectomy patients.
DESIGN
METHODS
Descriptive, based on medical record review.
SETTINGS
METHODS
Two tertiary care centers in Riyadh.
PATIENTS AND METHODS
METHODS
We included patients who underwent thyroid surgery from January 1, 2004 to December 31, 2016 who ranged in age from 9-90 years regardless of initial diagnosis.
MAIN OUTCOME MEASURES
METHODS
Distribution of thyroid carcinomas by type, age and sex and trends over the time period.
SAMPLE SIZE
METHODS
979 patients.
RESULTS
RESULTS
Of 979 patients, 84.5% were <55 years old, with the majority being female. Thyroid malignancy ranked second to benign tumors, and the most common type of thyroid cancer was papillary thyroid carcinoma (91% of malignant tumors), followed by follicular thyroid cancer (4.7% of malignant tumors). After thyroid microcarcinomas were isolated from the sample and studied separately, we found the overall trend for thyroid cancer to be stable, and that the annual increases in rates were due to increased diagnosis of thyroid microcarcinoma in the period from 2010 to 2016.
CONCLUSION
CONCLUSIONS
Our study shows that increases in thyroid cancers may be attributed to a rise in the rates of diagnosis of thyroid microcarcinomas.
LIMITATIONS
CONCLUSIONS
The main limitation is the retrospective nature of this design. Also, a multicenter collaboration would prove beneficial in evaluating the trends of thyroid cancer in Saudi Arabia on a much larger scale.
CONFLICT OF INTEREST
BACKGROUND
None.
Identifiants
pubmed: 31580696
doi: 10.5144/0256-4947.2019.345
pmc: PMC6832316
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
345-349Références
Thyroid. 2016 Nov;26(11):1541-1552
pubmed: 27571228
N Engl J Med. 2016 Aug 18;375(7):614-7
pubmed: 27532827
Int J Cancer. 2015 Dec 1;137(11):2664-73
pubmed: 26069163
Surgery. 2018 Jan;163(1):48-52
pubmed: 29103582
Int J Cancer. 2015 Mar 1;136(5):E359-86
pubmed: 25220842
Hematol Oncol Stem Cell Ther. 2013 Jun;6(2):58-64
pubmed: 23756719
CA Cancer J Clin. 2012 Mar-Apr;62(2):118-28
pubmed: 22281605
N Engl J Med. 2014 Nov 6;371(19):1765-7
pubmed: 25372084
J Immigr Minor Health. 2015 Jun;17(3):638-43
pubmed: 24859807
Endocr J. 2017 Mar 31;64(3):237-244
pubmed: 28154351
N Engl J Med. 2015 Dec 10;373(24):2389-90
pubmed: 26650173
Am J Clin Pathol. 2009 Nov;132(5):658-65
pubmed: 19846805
Thyroid. 2016 Jan;26(1):1-133
pubmed: 26462967
Thyroid. 2014 Jan;24(1):27-34
pubmed: 24001104