Update and review of adult polycystic kidney disease.

Autosomal dominant kidney disease End stage kidney disease Hypertension Kidney cyst Tolvaptan

Journal

Disease-a-month : DM
ISSN: 1557-8194
Titre abrégé: Dis Mon
Pays: United States
ID NLM: 0370657

Informations de publication

Date de publication:
May 2020
Historique:
pubmed: 5 10 2019
medline: 6 5 2020
entrez: 5 10 2019
Statut: ppublish

Résumé

Autosomal dominant polycystic kidney disease is a common cause of end stage kidney disease. It is a progressive and unfortunately incurable condition that can lead to significant morbidity and kidney failure. Many more patients are diagnosed with this disease without any symptoms as the population is increasingly undergoing imaging for other problems and diagnostic workup. Our understanding of the genetic variants has increased in recent years as research continues to improve. As well, therapeutic options have developed with the FDA approval of a new treatment medication, with many others underway. This review updates the clinician on the pathophysiology, clinical aspects, and therapeutic options for patients the is form of kidney disease.

Identifiants

pubmed: 31582186
pii: S0011-5029(19)30128-2
doi: 10.1016/j.disamonth.2019.100887
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

100887

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Gates B Colbert (GB)

Baylor University Medical Center at Dallas, TX, United States. Electronic address: gates.colbert@bswhealth.org.

Mohamed E Elrggal (ME)

Kidney and Urology Center, Alexandria, Egypt.

Lovy Gaur (L)

Max Superspeciality Hospitals, Vaishali, India.

Edgar V Lerma (EV)

UIC/Advocate Christ Medical Center, Oak Lawn, IL United States. Electronic address: nephron0@gmail.com.

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Classifications MeSH