Update and review of adult polycystic kidney disease.
Autosomal dominant kidney disease
End stage kidney disease
Hypertension
Kidney cyst
Tolvaptan
Journal
Disease-a-month : DM
ISSN: 1557-8194
Titre abrégé: Dis Mon
Pays: United States
ID NLM: 0370657
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
pubmed:
5
10
2019
medline:
6
5
2020
entrez:
5
10
2019
Statut:
ppublish
Résumé
Autosomal dominant polycystic kidney disease is a common cause of end stage kidney disease. It is a progressive and unfortunately incurable condition that can lead to significant morbidity and kidney failure. Many more patients are diagnosed with this disease without any symptoms as the population is increasingly undergoing imaging for other problems and diagnostic workup. Our understanding of the genetic variants has increased in recent years as research continues to improve. As well, therapeutic options have developed with the FDA approval of a new treatment medication, with many others underway. This review updates the clinician on the pathophysiology, clinical aspects, and therapeutic options for patients the is form of kidney disease.
Identifiants
pubmed: 31582186
pii: S0011-5029(19)30128-2
doi: 10.1016/j.disamonth.2019.100887
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
100887Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.