Pancreatic cyst surveillance imposes low psychological burden.
Early detection of cancer
Pancreatic cyst
Patient reported outcome measures
Psychology
Journal
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
ISSN: 1424-3911
Titre abrégé: Pancreatology
Pays: Switzerland
ID NLM: 100966936
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
24
04
2019
revised:
23
08
2019
accepted:
30
08
2019
pubmed:
5
10
2019
medline:
16
5
2020
entrez:
5
10
2019
Statut:
ppublish
Résumé
For the currently recommended pancreatic cyst surveillance to be feasible, participant adherence is a prerequisite. Our objective was to evaluate the psychological burden of pancreatic cyst surveillance from a participant's perspective. The present participant survey is part of an international cohort study (PACYFIC study, www.pacyfic.net), which prospectively records the outcome of surveillance of asymptomatic pancreatic cysts. Participants are invited to complete questionnaires before and during cyst surveillance. 109 participants, 31 enrolled before and 78 during surveillance (median time since cyst diagnosis 16.5 (IQR 36) months), returned a total of 179 questionnaires. The majority indicated that surveillance reduces concerns of developing pancreatic cancer (82%), gives a sense of certainty (81%) and is a good method to detect cancer (91%). Participants already undergoing surveillance reported more negative aspects than those still to commence, like sleeping worse (30% vs 13%, P = 0.035), postponing plans (32% vs 13%, P = 0.031), and finding the follow-up burdensome (33% vs 13%, P = 0.044). Overall, the vast majority (94%) deemed advantages to outweigh disadvantages. Anxiety and depression scores were low (median Hospital Anxiety and Depression Scale 4 for anxiety (IQR 6), 2 for depression (IQR 5)). The psychological burden of pancreatic cyst surveillance is low. Therefore, participant adherence is expected to be high and annual surveillance seems feasible.
Sections du résumé
BACKGROUND/OBJECTIVES
OBJECTIVE
For the currently recommended pancreatic cyst surveillance to be feasible, participant adherence is a prerequisite. Our objective was to evaluate the psychological burden of pancreatic cyst surveillance from a participant's perspective.
METHODS
METHODS
The present participant survey is part of an international cohort study (PACYFIC study, www.pacyfic.net), which prospectively records the outcome of surveillance of asymptomatic pancreatic cysts. Participants are invited to complete questionnaires before and during cyst surveillance.
RESULTS
RESULTS
109 participants, 31 enrolled before and 78 during surveillance (median time since cyst diagnosis 16.5 (IQR 36) months), returned a total of 179 questionnaires. The majority indicated that surveillance reduces concerns of developing pancreatic cancer (82%), gives a sense of certainty (81%) and is a good method to detect cancer (91%). Participants already undergoing surveillance reported more negative aspects than those still to commence, like sleeping worse (30% vs 13%, P = 0.035), postponing plans (32% vs 13%, P = 0.031), and finding the follow-up burdensome (33% vs 13%, P = 0.044). Overall, the vast majority (94%) deemed advantages to outweigh disadvantages. Anxiety and depression scores were low (median Hospital Anxiety and Depression Scale 4 for anxiety (IQR 6), 2 for depression (IQR 5)).
CONCLUSION
CONCLUSIONS
The psychological burden of pancreatic cyst surveillance is low. Therefore, participant adherence is expected to be high and annual surveillance seems feasible.
Identifiants
pubmed: 31582346
pii: S1424-3903(19)30719-7
doi: 10.1016/j.pan.2019.08.011
pii:
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
1061-1066Investigateurs
M J Bruno
(MJ)
D L Cahen
(DL)
P A van Riet
(PA)
K A Overbeek
(KA)
I J M Levink
(IJM)
B Koopmann
(B)
M G H Besselink
(MGH)
M Del Chiaro
(M)
M M Lerch
(MM)
M B Wallace
(MB)
M van Ballegooijen
(M)
K Biermann
(K)
E M A Bleiker
(EMA)
T H L Bollen
(THL)
P Fockens
(P)
I M C M de Kok
(IMCM)
L H J Looijenga
(LHJ)
M P Peppelenbosch
(MP)
J H E Verhagen-Oldenampsen
(JHE)
P G Arcidiacono
(PG)
G Capurso
(G)
J Bergmann
(J)
A van Berkel
(A)
G Beyer
(G)
R Bijlsma
(R)
H Braat
(H)
D L Cahen
(DL)
S Carrara
(S)
L Czakó
(L)
H van Erp-van der Steen
(H)
S Ganesh
(S)
E van Geenen
(E)
T Gonda
(T)
C Hoge
(C)
P Honkoop
(P)
J E van Hooft
(JE)
J Jansen
(J)
A Larghi
(A)
I van Leeuwenburgh
(I)
J Laukkarinen
(J)
N Lelyveld
(N)
M Lerch
(M)
M C di Marco
(MC)
C Ricci
(C)
R Casadei
(R)
E P Rau
(EP)
L Perk
(L)
M Polkowski
(M)
A Pukitits
(A)
R Quispel
(R)
D Radenkovic
(D)
A Seicean
(A)
T Schwartz
(T)
E J Schoon
(EJ)
E van Soest
(E)
A Tan
(A)
N G Venneman
(NG)
P Vos
(P)
A Voorburg
(A)
L A van der Waaij
(LA)
M B Wallace
(MB)
L R H Wijkerslooth
(LRH)
G Zerboni
(G)
G Capurso
(G)
G Della Fave
(G)
B Zonderhuis
(B)
Informations de copyright
Copyright © 2019 IAP and EPC. Published by Elsevier B.V. All rights reserved.