Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients.


Journal

Haematologica
ISSN: 1592-8721
Titre abrégé: Haematologica
Pays: Italy
ID NLM: 0417435

Informations de publication

Date de publication:
07 2020
Historique:
received: 08 04 2019
accepted: 26 09 2019
pubmed: 5 10 2019
medline: 28 4 2021
entrez: 5 10 2019
Statut: ppublish

Résumé

In some settings, cancer cells responding to treatment undergo an immunogenic form of cell death that is associated with the abundant emission of danger signals in the form of damage-associated molecular patterns. Accumulating preclinical and clinical evidence indicates that danger signals play a crucial role in the (re-)activation of antitumor immune responses

Identifiants

pubmed: 31582537
pii: haematol.2019.223933
doi: 10.3324/haematol.2019.223933
pmc: PMC7327638
doi:

Substances chimiques

Calreticulin 0
Interleukin-15 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1868-1878

Informations de copyright

Copyright© 2020 Ferrata Storti Foundation.

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Auteurs

Iva Truxova (I)

Sotio, Prague, Czech Republic.

Lenka Kasikova (L)

Sotio, Prague, Czech Republic.
Department of Immunology, Charles University, 2 Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

Cyril Salek (C)

Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
Institute of Clinical and Experimental Hematology, 1 Faculty of Medicine, Charles University, Prague, Czech Republic.

Michal Hensler (M)

Sotio, Prague, Czech Republic.

Daniel Lysak (D)

Department of Hematology and Oncology, University Hospital in Pilsen, Czech Republic.

Peter Holicek (P)

Sotio, Prague, Czech Republic.
Department of Immunology, Charles University, 2 Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

Pavla Bilkova (P)

Sotio, Prague, Czech Republic.

Monika Holubova (M)

Laboratory of Tumor Biology and Immunotherapy, Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.

Xiufen Chen (X)

Department of Medicine, University of Chicago, Chicago, IL, USA.

Romana Mikyskova (R)

Laboratory of Immunological and Tumour models, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.

Milan Reinis (M)

Laboratory of Immunological and Tumour models, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.

Marek Kovar (M)

Laboratory of Tumor Immunology, Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.

Barbora Tomalova (B)

Laboratory of Tumor Immunology, Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.

Justin P Kline (JP)

Department of Medicine, University of Chicago, Chicago, IL, USA.
Committee on Immunology, University of Chicago, Chicago, IL, USA.
University of Chicago Comprehensive Cancer Center, Chicago, IL, USA.

Lorenzo Galluzzi (L)

Department of Radiation Oncology, Weill Cornell Medical College, New York, NY, USA.
Sandra and Edward Meyer Cancer Center, New York, NY, USA.
Caryl and Israel Englander Institute for Precision Medicine, New York, NY, USA.
Department of Dermatology, Yale School of Medicine, New Haven, CT, USA.
Universite de Paris, Paris, France.

Radek Spisek (R)

Sotio, Prague, Czech Republic.
Department of Immunology, Charles University, 2 Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

Jitka Fucikova (J)

Sotio, Prague, Czech Republic fucikova@sotio.com.
Department of Immunology, Charles University, 2 Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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Classifications MeSH