Gastric polyposis and desmoid tumours as a new familial adenomatous polyposis clinical variant associated with


Journal

Journal of medical genetics
ISSN: 1468-6244
Titre abrégé: J Med Genet
Pays: England
ID NLM: 2985087R

Informations de publication

Date de publication:
05 2020
Historique:
received: 22 05 2019
revised: 04 09 2019
accepted: 07 09 2019
pubmed: 9 10 2019
medline: 12 6 2021
entrez: 9 10 2019
Statut: ppublish

Résumé

Germline mutations of the APC gene, which encodes a multidomain protein of 2843 amino acid residues, cause familial adenomatous polyposis (FAP). Three FAP clinical variants are correlated with the location of

Identifiants

pubmed: 31591141
pii: jmedgenet-2019-106299
doi: 10.1136/jmedgenet-2019-106299
pmc: PMC7231465
doi:

Substances chimiques

APC protein, human 0
Adenomatous Polyposis Coli Protein 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

356-360

Informations de copyright

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

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Auteurs

Vittoria Disciglio (V)

Medical Genetics, National Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.

Candida Fasano (C)

Medical Genetics, National Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.

Filomena Cariola (F)

Medical Genetics, National Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.

Giovanna Forte (G)

Medical Genetics, National Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.

Valentina Grossi (V)

Medical Genetics, National Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.

Paola Sanese (P)

Medical Genetics, Department of Biomedical Sciences and Human Oncology (DIMO), University of Bari "Aldo Moro", Bari, Italy.

Martina Lepore Signorile (M)

Medical Genetics, National Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.
Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.

Nicoletta Resta (N)

Medical Genetics, Department of Biomedical Sciences and Human Oncology (DIMO), University of Bari "Aldo Moro", Bari, Italy.

Claudio Lotesoriere (C)

Department of Oncology, National Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy.

Alessandro Stella (A)

Medical Genetics, Department of Biomedical Sciences and Human Oncology (DIMO), University of Bari "Aldo Moro", Bari, Italy.

Ivan Lolli (I)

Department of Oncology, National Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy cristianosimone73@gmail.com ivan.lolli@irccsdebellis.it.

Cristiano Simone (C)

Medical Genetics, National Institute of Gastroenterology "S. de Bellis", Research Hospital, Castellana Grotte, Italy cristianosimone73@gmail.com ivan.lolli@irccsdebellis.it.
Medical Genetics, Department of Biomedical Sciences and Human Oncology (DIMO), University of Bari "Aldo Moro", Bari, Italy.

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Classifications MeSH