Establishment of xenografts of urological cancers on chicken chorioallantoic membrane (CAM) to study metastasis.
animal mode
bladder cancer
chorioallantoic membrane
kidney cancer
prostate cancer
Journal
Precision clinical medicine
ISSN: 2516-1571
Titre abrégé: Precis Clin Med
Pays: England
ID NLM: 101739592
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
11
07
2019
revised:
23
08
2019
accepted:
26
08
2019
entrez:
11
10
2019
pubmed:
11
10
2019
medline:
11
10
2019
Statut:
ppublish
Résumé
Cancer of the urological system commonly occurs in the kidney, bladder, and prostate gland. The clear cell subtype of renal cell carcinoma (ccRCC) constitutes the great majority of kidney cancer. Metastatic ccRCC portends a very poor outcome with no effective treatment available. Prostate cancer is the most common cancer in males in the US. Despite recent advances in selective kinase inhibitors and immunotherapies, the rate of developing new treatment from bench to bedside is slow. A time-consuming step is at the animal drug testing stage, in which the mouse model is the gold standard. In the pursuit to streamline the
Identifiants
pubmed: 31598385
doi: 10.1093/pcmedi/pbz018
pii: pbz018
pmc: PMC6770283
doi:
Types de publication
Journal Article
Langues
eng
Pagination
140-151Subventions
Organisme : NCI NIH HHS
ID : P30 CA016042
Pays : United States
Organisme : NCI NIH HHS
ID : R21 CA216770
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001881
Pays : United States
Informations de copyright
© The Author(s) 2019. Published by Oxford University Press on behalf of West China School of Medicine & West China Hospital of Sichuan University.
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